Nanomaterials as promising alternative in the infection treatment



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Vallet Regí, María and González Ortiz, Blanca and Izquierdo-Barba, Isabel (2019) Nanomaterials as promising alternative in the infection treatment. International Journal of Molecular Sciences, 20 (15). p. 3806. ISSN 1661-6596 (In Press)

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Both the prevalence of antibiotic resistance and the increased biofilm-associated infections are boosting the demand for new advanced and more effective treatment for such infections. In this sense, nanotechnology offers a ground-breaking platform for addressing this challenge. This review shows the current progress in the field of antimicrobial inorganic-based nanomaterials and their activity against bacteria and bacterial biofilm. Herein, nanomaterials preventing the bacteria adhesion and nanomaterials treating the infection once formed are presented through a classification based on their functionality. To fight infection, nanoparticles with inherent antibacterial activity and nanoparticles acting as nanovehicles are described, emphasizing the design of the carrier nanosystems with targeting properties towards the bacteria and the biofilm.

Item Type:Article
Additional Information:

RESEARCHER ID M-3378-2014 (María Vallet Regí)
ORCID 0000-0002-6104-4889 (María Vallet Regí)
RESEARCHER ID K-4773-2015 (Blanca González Ortiz)
ORCID 0000-0002-0493-6071 (Blanca González Ortiz)
RESEARCHER ID M-9921-2014 (Isabel Izquierdo Barba)
ORCID 0000-0002-4139-4646 (Isabel Izquierdo Barba)

Uncontrolled Keywords:Preventing infection; Zwitterionic surfaces; Nanopattering surfaces; Nanoparticles; Mesoporous silica nanoparticles, Antibacterial activity; Targeting
Subjects:Sciences > Chemistry > Materials
Medical sciences > Pharmacy > Inorganic chemistry
ID Code:56883
Deposited On:04 Oct 2019 07:41
Last Modified:04 Oct 2019 10:46

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