Publication: PET amiloide en la esclerosis múltiple
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2019-11-12
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Universidad Complutense de Madrid
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Abstract
La esclerosis múltiple (EM) es la enfermedad desmielinizante más frecuente y la primera causa de discapacidad neurológica no traumática en adultos jóvenes. Es clínicamente heterogénea, incluye síntomas motores, cognitivos y fatiga. Esto es el resultado de una combinación de los principales procesos fisiopatológicos involucrados: inflamación, desmielinización, daño axonal y neurodegeneración. En los últimos años, se han desarrollado distintas terapias modificadoras de la enfermedad, dirigidas a actuar sobre el sistema inmunitario, con un efecto antiinflamatorio, que tienen por objetivo de intentar prevenir las recaídas y ralentizar la progresión de la discapacidad...
Multiple sclerosis (MS) is the most common demyelinating disease and the main cause of non-traumatic neurological disability in young adults. It is a clinically heterogeneous disease, including motor, cognitive and fatigue symptoms. This is the result of a combination of the main pathophysiological processes involved: inflammation, demyelination, axonal damage and neurodegeneration. In recent years, various disease-modifying therapies have been developed, aimed at acting on the immune system, with an anti-inflammatory effect that prevents relapses and slows the progression of disability...
Multiple sclerosis (MS) is the most common demyelinating disease and the main cause of non-traumatic neurological disability in young adults. It is a clinically heterogeneous disease, including motor, cognitive and fatigue symptoms. This is the result of a combination of the main pathophysiological processes involved: inflammation, demyelination, axonal damage and neurodegeneration. In recent years, various disease-modifying therapies have been developed, aimed at acting on the immune system, with an anti-inflammatory effect that prevents relapses and slows the progression of disability...
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Tesis inédita de la Universidad Complutense de Madrid, Facultad de Medicina, leída el 30-09-2019