Publication: Relación entre la volumetría esplácnica abdominal medida por TAC y variables pronósticas en pacientes con cirrosis
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2019-11-14
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Universidad Complutense de Madrid
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Abstract
La determinación de la volumetría visceral abdominal a través de pruebas de imagen es una técnica estandarizada y con aplicaciones crecientes. Se conoce que los cambios morfológicos en el hígado y el bazo son característicos en la historia natural de la enfermedad hepática crónica avanzada. Sin embargo, las correlaciones entre el volumen hepático total, los volúmenes segmentarios y el volumen del bazo y las variables clínicas, hemodinámicas, de laboratorio e histológicas que marcan el pronóstico en la enfermedad es desconocida.Objetivos: 1) Estudiar la asociación entre el volumen hepático total y segmentario y el volumen esplénico y las variables con valor pronóstico en la enfermedad hepática avanzada. 2) Determinar la capacidad diagnostica de la volumetría esplácnica abdominal determinada por tomografía axial computarizada (TC) para detectar hipertensión portal clínicamente significativa (HPCS)...
Evaluation of visceral volumes by imaging procedures is a well standardized technique with increasing applications. There is available evidence suggesting the association between morphological changes and the natural history of cirrhosis. However, the relationship of standardized liver volume with hemodynamic, clinical and histological variables in cirrhosis is unknown.Aims: 1) To study the association between total and segmental liver and spleen volume and prognostic variables in cirrhosis and 2) to assess its diagnostic accuracy in the evaluation of clinically significant portal hypertension (CSPH).Methods: We included 185 patients with cirrhosis and CT (147 had simultaneous HVPG) who received liver transplantation or hepatic resection...
Evaluation of visceral volumes by imaging procedures is a well standardized technique with increasing applications. There is available evidence suggesting the association between morphological changes and the natural history of cirrhosis. However, the relationship of standardized liver volume with hemodynamic, clinical and histological variables in cirrhosis is unknown.Aims: 1) To study the association between total and segmental liver and spleen volume and prognostic variables in cirrhosis and 2) to assess its diagnostic accuracy in the evaluation of clinically significant portal hypertension (CSPH).Methods: We included 185 patients with cirrhosis and CT (147 had simultaneous HVPG) who received liver transplantation or hepatic resection...
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Tesis inédita de la Universidad Complutense de Madrid, Facultad de Medicina, leída el 10-07-2019