Publication: Liposomas y polímeros bioadhesivos para el tratamiento de la enfermedad del ojo seco
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2019-11-21
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Universidad Complutense de Madrid
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Abstract
La enfermedad de ojo seco (EOS) se considera una patología multifactorial que cursa con sequedad o quemazón de la superficie ocular con una prevalencia comprendida entre el 5 y el 50% de la población mundial. La hiperosmolaridad y la inestabilidad de la película lagrimal constituyen los mecanismos principales dela fisiopatología del EOS. Recientemente se ha postulado que las trampas extracelulares de neutrófilos (NET) están involucrados en la patogénesis de la enfermedad...
Dry eye disease (DED) is a prevalent and multifactorial pathology of the ocular surface affecting 5-50% of the world’s population. The disease is characterized by a loss of homeostasis of the tear film and it may manifest with ocular symptoms such as dryness and burning. Tear hyperosmolarity and tear film instability constitute the core mechanisms in DED pathophysiology. Recently, neutrophilextracellular traps (NETs) have also been postulated to play a role in the pathogenesis of the disease..
Dry eye disease (DED) is a prevalent and multifactorial pathology of the ocular surface affecting 5-50% of the world’s population. The disease is characterized by a loss of homeostasis of the tear film and it may manifest with ocular symptoms such as dryness and burning. Tear hyperosmolarity and tear film instability constitute the core mechanisms in DED pathophysiology. Recently, neutrophilextracellular traps (NETs) have also been postulated to play a role in the pathogenesis of the disease..
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Tesis inédita de la Universidad Complutense de Madrid, Facultad de Farmacia, Departamento de Farmacia Galénica y Tecnología Alimentaria, leída el 28-06-2019