Ultrasound-activated nanomaterials for therapeutics



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Paris, J.L. and Vallet Regí, María (2020) Ultrasound-activated nanomaterials for therapeutics. Bulletin of The Chemical Society of Japan, 93 (2). pp. 220-229. ISSN 1348-0634

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Official URL: https://doi.org/10.1246/bcsj.20190346


Ultrasound has attracted much attention in recent years as an external stimulus capable of activating different types of nanomaterials for therapeutic application. One of the characteristics that makes ultrasound an especially appealing triggering stimulus for nanomedicine is its capacity to be non-invasively applied in a focused manner at deep regions of the body. Combining ultrasound with nanoparticles, different biological effects can be achieved. In this work, an overview of the four main types of inducible responses will be provided: inducing drug release, producing ultrasound-derived biological effects, modifying nanoparticle biodistribution and developing theranostic agents. Several examples of each one of these applications are presented here to illustrate the key concepts underlying recent developments in the discipline.

Item Type:Article
Additional Information:

RESEARCHER ID D-9318-2017 (Juan Luis Paris de la Fuente)
ORCID 0000-0001-8950-283X (Juan Luis Paris de la Fuente)
RESEARCHER ID M-3378-2014 (María Vallet Regí)
ORCID 0000-0002-6104-4889 (María Vallet Regí)

Uncontrolled Keywords:Ultrasound, Nanomedicine, Stimuli-responsive
Subjects:Sciences > Chemistry > Materials
Medical sciences > Pharmacy > Inorganic chemistry
ID Code:58438
Deposited On:10 Feb 2020 12:58
Last Modified:26 Feb 2021 11:01

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