Publication: Conciencia de enfermedad en esquizofrenia: relación con sintomatología y cognición
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2020-01-14
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Universidad Complutense de Madrid
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Abstract
El déficit en la conciencia de enfermedad es frecuente en los pacientes con esquizofrenia. En la actualidad, los modelos que conciben esta conciencia de enfermedad como una entidad multidimensional han sido ampliamente aceptados. Diferentes trabajos apuntan a que un déficit en la conciencia de enfermedad se asocia con una peor situación clínica, una menor adherencia al tratamiento, y un peor funcionamiento global. Dada la relevancia de este déficit, diversos estudios previos han analizado su posible relación con la sintomatología clínica y la cognición. Estos trabajos han puesto de manifiesto que, en los pacientes con esquizofrenia, la conciencia de enfermedad presenta una relación con la sintomatología y con la cognición. Sin embargo, muchos de estos estudios se han realizado con pequeños tamaños muestrales, con pacientes con diagnósticos heterogéneos, y con abordajes estadísticos que no permiten estudiar de manera concurrente las relaciones existentes entre diferentes variables dependientes e independientes...
Illness unawareness, or lack of insight, is a common feature of schizophrenia. Multidimensional models of insight have been widely accepted, while dIfferent studies suggest that illness unawareness is associated with a less favorable prognosis, less treatment adherence, and worse functioning. Given the relevance of lack of insight, several studies have investigated possible associations of insight with other important manifestations of the disorder such as clinical symptoms and cognition. Previous studies show that a relationship exists between insight, symptoms and cognition. However, previous studies often include small samples and patients with heterogeneous diagnoses. In addition, most studies use statistical methods that do not allow for simultaneous testing of existing relationships among symptoms and cognition, as well as both their relationships with insight...
Illness unawareness, or lack of insight, is a common feature of schizophrenia. Multidimensional models of insight have been widely accepted, while dIfferent studies suggest that illness unawareness is associated with a less favorable prognosis, less treatment adherence, and worse functioning. Given the relevance of lack of insight, several studies have investigated possible associations of insight with other important manifestations of the disorder such as clinical symptoms and cognition. Previous studies show that a relationship exists between insight, symptoms and cognition. However, previous studies often include small samples and patients with heterogeneous diagnoses. In addition, most studies use statistical methods that do not allow for simultaneous testing of existing relationships among symptoms and cognition, as well as both their relationships with insight...
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Tesis inédita de la Universidad Complutense de Madrid, Facultad de Medicina, Departamento de Psiquiatría, leída el 08-11-2019