Publication: Factores asociados con el desarrollo de hipertensión pulmonar en pacientes con un tromboembolismo pulmonar agudo
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2020-02-17
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Universidad Complutense de Madrid
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Abstract
El tromboembolismo pulmonar (TEP) se define como el enclavamiento de un émbolo en las arterias pulmonares desprendido de cualquier parte del territorio venoso, generalmente de una trombosis venosa profunda de miembros inferiores, aunque su origen puede ser diverso (extremidades superiores, venas uterinas, prostáticas, renales o cavidades derechas). En las últimas décadas, se ha convertido en uno de los principales problemas de salud pública, pese a que su prevalencia es menor que la de otras enfermedades cardiovasculares como el infarto de miocardio o la enfermedad cerebrovascular. A pesar de ello, su gravedad es similar y las complicaciones posteriores cuando el cuadro no se resuelve pueden ser igualmente mortales si no se diagnostican de forma precoz, como es el caso de la hipertensión pulmonar tromboembólica crónica (HPTEC). Por ello, muchos esfuerzos se centran en identificar en el momento agudo del TEP, características clínicas o marcadores que permitan distinguir qué pacientes presentan un riesgo mayor de padecer estas complicaciones. Uno de estos marcadores es la presencia de hipertensión pulmonar en el momento de diagnóstico...
Pulmonary thromboembolism (PTE) is defined as the clogging of anembolus in the pulmonary arteries released from any part of the venous territory, usually from a deep venous thrombosis of the lower limbs, although its origin may be diverse (upper limbs, uterine veins, prostate, renal or right cardiac chambers). In recent decades, it has become one of the main public health problems, although its prevalence is lower than other cardiovascular diseases such as myocardial infarction or cerebrovascular disease. However, its severity and subsequent complications are similar when the condition is not resolved and can be equally fatal if not diagnosed early, as is the case with chronic thromboembolic pulmonary hypertension (PH). Therefore, many efforts are focused on identifying clinical features or markers at the acute moment of illness that can distinguish which patients are at higher risk ofthese complications. One of these markers is pulmonary hypertension at the time of diagnosis...
Pulmonary thromboembolism (PTE) is defined as the clogging of anembolus in the pulmonary arteries released from any part of the venous territory, usually from a deep venous thrombosis of the lower limbs, although its origin may be diverse (upper limbs, uterine veins, prostate, renal or right cardiac chambers). In recent decades, it has become one of the main public health problems, although its prevalence is lower than other cardiovascular diseases such as myocardial infarction or cerebrovascular disease. However, its severity and subsequent complications are similar when the condition is not resolved and can be equally fatal if not diagnosed early, as is the case with chronic thromboembolic pulmonary hypertension (PH). Therefore, many efforts are focused on identifying clinical features or markers at the acute moment of illness that can distinguish which patients are at higher risk ofthese complications. One of these markers is pulmonary hypertension at the time of diagnosis...
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Tesis inédita de la Universidad Complutense de Madrid, Facultad de Medicina, Departamento de Medicina, leída el 28-11-2019