Thermomechanical Transitions of Egg-Ceramide Monolayers



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Catapano, Elisa R. and Lillo, M. P. and García Rodríguez, C. and Natale, Paolo and Langevin, D. and Monroy Muñoz, Francisco and López-Montero, Iván (2015) Thermomechanical Transitions of Egg-Ceramide Monolayers. Langmuir, 31 (13). pp. 3912-3918. ISSN 0743-7463

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Ceramides have unique biophysical properties. Their high melting temperature and their ability to form lateral domains have converted ceramides into the paradigm of rigid lipids. Here, using shear surface rheology of egg-ceramide Langmuir monolayers, a solid to fluid transition was evidenced as a vanishing shear rigidity at lower temperatures than the lipid melting temperature. Such a mechanical transition, which depends on the lipid lateral pressure, was found in a broad range temperature (40−50 °C). The solid to fluid transition was correlated to a LC to LC+LE phase transition, as confirmed by BAM experiments. Interestingly, together with the softening transition, a supercooling process compatible with a glassy behavior was found upon freezing. A new phase scenario is then depicted that broadens the mechanical behavior of natural ceramides. The phase diversity of ceramides might have important implications in their physiological roles.

Item Type:Article
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The research leading to these results has received funding from the European Research Council under the European Union's Seventh Framework Programme (ERC grant agreement n° 338133)

Uncontrolled Keywords:Lipids; Monolayers; Compression; Fluids; Phase transitions
Subjects:Sciences > Chemistry > Chemistry, Physical and theoretical
ID Code:60104
Deposited On:22 Apr 2020 17:35
Last Modified:22 Apr 2020 17:35

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