Spectrum of Headaches Associated With SARS‐CoV‐2 Infection: Study of Healthcare Professionals



Downloads per month over past year

Porta-Etessam, Jesús and Matias Guiu, Jordi A. and González García, Nuria and Gómez Iglesias, Patricia and Santos Bueso, Enrique and Arriola Villalobos, Pedro and García Azorín, David and Matias Guiu, Jorge (2020) Spectrum of Headaches Associated With SARS‐CoV‐2 Infection: Study of Healthcare Professionals. Headache, 60 . pp. 1697-1704. ISSN 0017-8748

[thumbnail of Libre acceso en la web del editor]
PDF (Libre acceso en la web del editor)

Official URL: https://doi.org/10.1111/head.13902


Background: Series of patients with SARS‐CoV‐2 infection report headache in 6%‐15% of cases, although some data suggest that the actual frequency is higher, and that headache is not associated with fever. No study published to date has analyzed the characteristics of headache in these patients.
Objective: To analyze the characteristics of COVID‐19 related headaches.
Methods: We conducted a survey of Spaniard healthcare professionals who have been infected by SARS‐CoV‐2 and presented headache during the course of the disease. The survey addressed respondents’ medical history and headache characteristics, and we analyzed the association between both.
Results: We analyzed the responses of a sample of 112 healthcare professionals. History of migraine was reported by 20/112 (17.9%) of respondents, history of tension‐type headache by 8/112 (7.1%), and history of cluster headache was reported by a single respondent; 82/112(73.2%) of respondents had no history of headache. Headache presented independently of fever, around the third day after symptom onset. The previous history of migraine was associated with a higher frequency of pulsating headache (20% in patients with previous migraine vs 4.3% in those with no history of migraine, P = .013).
Conclusion: Headache is often holocranial, hemicranial, or occipital, pressing, and worsens with physical activity or head movements. Because the characteristics of the headache and the associated symptoms are heterogeneous in our survey, we suggest that several patterns with specific pathophysiological mechanisms may underlie the headache associated with COVID‐19.

Item Type:Article
Additional Information:

Artículo de libre acceso en la web del editor

Uncontrolled Keywords:COVID-19, SARS-CoV-2, headache, migraine, neurological symptoms, healthcare professionals
Subjects:Medical sciences > Medicine > Communicable diseases
Medical sciences > Medicine > Neurosciences
Medical sciences > Medicine > Ophtalmology
ID Code:61961
Deposited On:18 Nov 2020 15:49
Last Modified:06 Apr 2021 09:09

Origin of downloads

Repository Staff Only: item control page