In vitro Comparative Study of Fibroblastic Behaviour on Polymethacrylate (PMMA) and Lithium Disilicate Polymer Surfaces



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Herráez-Galindo, Cristina and Rizo-Gorrita, María and Luna-Oliva, Irene and Serrera-Figallo, María-Ángeles and Castillo Oyagüe, Raquel and Torres-Lagares, Daniel (2019) In vitro Comparative Study of Fibroblastic Behaviour on Polymethacrylate (PMMA) and Lithium Disilicate Polymer Surfaces. Polymers, 11 (4). p. 744. ISSN 2073-4360

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Polymethyl methacrylate (PMMA) and lithium disilicate are widely used materials in the dental field. PMMA is mainly used for the manufacture of removable prostheses; however, with the incorporation of CAD-CAM technology, new applications have been introduced for this material, including as a provisional implant attachment. Lithium disilicate is considered the gold standard for definitive attachment material. On the other hand, PMMA has begun to be used in clinics as a provisional attachment until the placement of a definitive one occurs. Although there are clinical studies regarding its use, there are few studies on cell reorganization around this type of material. This is why we carried out an in vitro comparative study using discs of both materials in which human gingival fibroblasts (HGFs) were cultured. After processing them, we analyzed various cellular parameters (cell count, cytoskeleton length, core size and coverage area). We analyzed the surface of the discs together with their composition. The results obtained were mostly not statistically significant, which shows that the qualities of PMMA make it a suitable material as an implant attachment.

Item Type:Article
Uncontrolled Keywords:Polymethyl methacrylate (PMMA); cytomorphometry; lithium silicate; gingival fibroblast; computer-aided design/computer-aided manufacturing (CAD/CAM); early cell proliferation
Subjects:Medical sciences > Dentistry
Medical sciences > Dentistry > Dental materials
ID Code:62448
Deposited On:07 Oct 2020 14:47
Last Modified:07 Oct 2020 14:47

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