Publication: Influencia del control químico como adyuvante al tratamiento mecánico en el manejo de la gingivitis y mucositis periimplantaria.
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2020
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Abstract
Objetivo: El objetivo de este estudio es evaluar la eficacia de un colutorio con clorhexidina (CHX) al 0,03% combinado con cloruro cetilpiridinio (CPC) al 0,05% como coadyuvante a la terapia mecánica para el tratamiento de la gingivitis y mucositis periimplantaria.
Material y métodos: Pacientes con presencia de al menos un implante con mucositis periimplantaria se incluyeron en este ensayo clínico aleatorizado. Los pacientes recibieron una profilaxis profesional en basal y a los seis meses y fueron instruidos para realizar un correcto control del biofilm mecánico y usar el colutorio o el placebo dos veces al día durante un año.
Resultados: En la presente publicación se aportan los resultados de las variables clínicas a boca completa. Ambos grupos de tratamiento muestran una reducción estadísticamente significativa en las variables clínicas en el tiempo, pero el efecto del grupo no siempre resulta estadísticamente significativo.
Conclusión: No se espera un beneficio adicional tras el uso del colutorio con CHX al 0,03% y CPC al 0,05% como coadyuvante a la terapia mecánica a nivel de boca completa.
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Trabajo Fin de Master encuadrado en la línea de investigación Etiología y Patogenia de las enfermedades periodontales y periimplantarias.
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Unesco subjects
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AAP 1996. Consensus report. Periodontal diseases: pathogenesis and microbial factors. Ann Periodontol. 1996;1(1):926-932.
• Albandar, JM, Susin, C, Hughes, FJ. Manifestations of systemic diseases and conditions that affect the periodontal attachment apparatus: Case definitions and diagnostic considerations. J Clin Periodontol. 2018; 45( Suppl 20): S171– S189.
• Araujo, MG, Lindhe, J. Peri‐implant health. J Periodontol. 2018; 89( Suppl 1): S249– S256. • Armitage GC. Development of a classification system for periodontal diseases and conditions. Ann Periodontol. 1999;4(1):1-6.
• Axelsson, P. (2004). Preventive Materials, Methods and Programs, Vol 4. London: Quintessence, pp. 37–102.
• Bascones A, Morante S, Mateos L, Mata M, Poblet J. Influence of additional active ingredients on the effectiveness of non-alcoholic chlorhexidine mouthwashes: a randomized controlled trial. J Periodontol. 2005;76(9):14691475.
• Billings, M, Holtfreter, B, Papapanou, PN, Mitnik, GL, Kocher, T, Dye, BA. Age‐dependent distribution of periodontitis in two countries: Findings from NHANES 2009 to 2014 and SHIP‐TREND 2008 to 2012. J Clin Periodontol. 2018; 45( Suppl 20): S130– S148.
• Bollain, J., Pulcini, A., Sanz-Sánchez, I. et al. Efficacy of a 0.03% chlorhexidine and 0.05% cetylpyridinium chloride mouth rinse in reducing inflammation around the teeth and implants: a randomized clinical trial. Clin Oral Invest (2020).
• Carcuac, O, Derks, J, Abrahamsson, I, Wennström, JL, Petzold, M, Berglundh, T. Surgical treatment of peri‐implantitis: 3‐year results from a randomized controlled clinical trial. J Clin Periodontol. 2017; 44: 1294– 1303.
• Chapple, ILC, Van der Weijden, F, Doerfer, C, Herrera, D, Shapira, L, Polak, D, Madianos, P, Louropoulou, A, Machtei, E, Donos, N, Greenwell, H, Van Winkelhoff, AJ, Eren Kuru, B, Arweiler, N, Teughels, W, Aimetti, M, Molina, A, Montero, E, Graziani, F. Primary prevention of periodontitis: managing gingivitis. J Clin Periodontol 2015; 42 (Suppl. 16): S71– S76.
• Cosgarea R, Sculean A, Shibli JA, Salvi GE (2019). Prevalence of peri-implant diseases – a critical review on the current evidence. Brazilian Oral Research, 33(Suppl. 1), e063. Epub September 30, 2019
• Costa FO, Takenaka-Martinez S, Cota LO, Ferreira SD, Silva GL, Costa JE. Periimplant disease in subjects with and without preventive maintenance: a 5-year follow-up. J Clin Periodontol. 2012;39(2):173-181.
• Derks J, Tomasi C. Peri-implant health and disease. A systematic review of current epidemiology. J Clin Periodontol. 2015;42 Suppl 16:S158-S171.
• Dreyer, H, Grischke, J, Tiede, C, et al. Epidemiology and risk factors of periimplantitis: A systematic review. J Periodont Res. 2018; 53: 657‐ 681.
• Ercoli, C, Caton, JG. Dental prostheses and tooth‐related factors. J Periodontol. 2018; 89( Suppl 1): S223– S236. • Ericsson I, Berglundh T, Marinello C, Liljenberg B, Lindhe J. Long-standing plaque and gingivitis at implants and teeth in the dog. Clin Oral Implants Res. 1992;3(3):99-103.
• Escribano M, Figuero E, Martín C, et al. Efficacy of adjunctive anti-plaque chemical agents: a systematic review and network meta-analyses of the Turesky modification of the Quigley and Hein plaque index. J Clin Periodontol. 2016;43(12):1059-1073.
• Ferreira, S.D., Silva, G.L.M., Cortelli, J.R., Costa, J.E. and Costa, F.O. (2006), Prevalence and risk variables for peri‐implant disease in Brazilian subjects. Journal of Clinical Periodontology, 33: 929-935.
• Figuero E, Herrera D, Tobías A, et al. Efficacy of adjunctive anti-plaque chemical agents in managing gingivitis: A systematic review and network meta-analyses. J Clin Periodontol. 2019;46(7):723-739.
• Fine, DH, Patil, AG, Loos, BG. Classification and diagnosis of aggressive periodontitis. J Clin Periodontol. 2018; 45( Suppl 20): S95– S111.
• Frencken JE, Sharma P, Stenhouse L, Green D, Laverty D, Dietrich T. Global epidemiology of dental caries and severe periodontitis – a comprehensive review. J Clin Periodontol. 2017;44(Suppl. 18): S94– S105.
• Gunsolley JC. A meta-analysis of six-month studies of antiplaque and antigingivitis agents. J Am Dent Assoc. 2006;137(12):1649-1657.
• Gunsolley, J. C. 2010. Clinical efficacy of antimicrobial mouthrinses. J Dent, 38 Suppl 1, S6-10.
• Haffajee AD, Socransky SS. Microbial etiological agents of destructive periodontal diseases. Periodontol 2000. 1994;5:78-111.
• Hajishengallis G, Liang S, Payne MA, et al. Low-abundance biofilm species orchestrates inflammatory periodontal disease through the commensal microbiota and complement. Cell Host Microbe. 2011;10(5):497-506.
• Hämmerle, CHF, Tarnow, D. The etiology of hard‐ and soft‐tissue deficiencies at dental implants: A narrative review. J Clin Periodontol. 2018; 45( Suppl 20): S267– S277. • Heitz‐Mayfield, LJA, Salvi, GE. Peri‐implant mucositis. J Clin Periodontol. 2018; 45( Suppl 20): S237– S245.
• Herrera, D., Roldán, S., Santacruz, I., Santos, S., Masdevall, M. and Sanz, M. (2003), Differences in antimicrobial activity of four commercial 0.12% chlorhexidine mouthrinse formulations: an in vitro contact test and salivary bacterial counts study. Journal of Clinical Periodontology, 30: 307-314.
• Herrera, D, Retamal‐Valdes, B, Alonso, B, Feres, M. Acute periodontal lesions (periodontal abscesses and necrotizing periodontal diseases) and endoperiodontal lesions. J Clin Periodontol. 2018; 45( Suppl 20): S78– S94.
• Holmstrup, P, Plemons, J, Meyle, J. Non–plaque‐induced gingival diseases. J Clin Periodontol. 2018; 45( Suppl 20): S28– S43. • Huang S, Li R, Zeng X, et al. Predictive modeling of gingivitis severity and susceptibility via oral microbiota. ISME J. 2014;8(9):1768-1780.
• Hujoel PP, Löe H, Anerud A, Boysen H, Leroux BG. Forty-five-year tooth survival probabilities among men in Oslo, Norway [published correction appears in J Dent Res 1999 Mar;78(3):815]. J Dent Res. 1998;77(12):2020-2027.
• James P, Worthington HV, Parnell C, et al. Chlorhexidine mouthrinse as an adjunctive treatment for gingival health. Cochrane Database Syst Rev. 2017;3(3):CD008676. Published 2017 Mar 31.
• Jepsen, S, Berglundh, T, Genco, R, Aass, AM, Demirel, K, Derks, J, Figuero, E, Giovannoli, JL, Goldstein, M, Lambert, F, Ortiz‐Vigon, A, Polyzois, I, Salvi, GE, Schwarz, F, Serino, G, Tomasi, C, Zitzmann, NU. Primary prevention of peri‐implantitis: managing peri‐implant mucositis. J Clin Periodontol 2015; 42 (Suppl. 16): S152– S157.
• Jepsen, S, Caton, JG, et al. Periodontal manifestations of systemic diseases and developmental and acquired conditions: Consensus report of workgroup 3 of the
2017 World Workshop on the Classification of Periodontal and Peri‐Implant Diseases and Conditions. J Clin Periodontol. 2018; 45( Suppl 20): S219– S229.
• Kistler JO, Booth V, Bradshaw DJ, Wade WG. Bacterial community development in experimental gingivitis. PLoS One. 2013;8(8):e71227. Published 2013 Aug 14.
• Lang NP, Adler R, Joss A, Nyman S. Absence of bleeding on probing. An indicator of periodontal stability. J Clin Periodontol. 1990;17(10):714-721.
• Lang, NP, Bartold, PM. Periodontal health. J Periodontol. 2018; 89 (Suppl 1): S9– S16. • Lee CT, Huang YW, Zhu L, Weltman R. Prevalences of peri-implantitis and periimplant mucositis: systematic review and meta-analysis. J Dent. 2017;62:1-12.
• Liljenberg B, Gualini F, Berglundh T, Tonetti M, Lindhe J. Composition of plaque-associated lesions in the gingiva and the peri-implant mucosa in partially edentulous subjects. J Clin Periodontol. 1997;24(2):119-123.
• Lobene RR. Effect of dentifrices on tooth stains with controlled brushing. J Am Dent Assoc. 1968;77(4):849-855. • Theilade, E., Wright, W.H., Jensen, S.B. and Löe, H. (1966), Experimental gingivitis in man. Journal of Periodontal Research, 1: 1-13.
• Mackenzie, I.C. and Tonetti, M.S. (1995), Formation of Normal Gingival Epithelial Phenotypes Around Osseo‐Integrated Oral Implants in Humans. Journal of Periodontology, 66: 933-943.
• Matuliene G, Studer R, Lang NP, et al. Significance of Periodontal Risk Assessment in the recurrence of periodontitis and tooth loss. J Clin Periodontol. 2010;37(2):191-199.
• Monje A, Aranda L, Diaz KT, et al. Impact of Maintenance Therapy for the Prevention of Peri-implant Diseases: A Systematic Review and Meta-analysis. J Dent Res. 2016;95(4):372-379.
• Murakami S, , Mealey, BL, Mariotti, A, Chapple, ILC. Dental plaque–induced gingival conditions. J Clin Periodontol. 2018; 45( Suppl 20): S17– S27. • Mombelli A, van Oosten MA, Schurch E Jr, Land NP. The microbiota associated with successful or failing osseointegrated titanium implants. Oral Microbiol Immunol. 1987;2(4):145-151.
• Mühlemann HR, Son S. Gingival sulcus bleeding--a leading symptom in initial gingivitis. Helv Odontol Acta. 1971;15(2):107-113.
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• Needleman, I, Garcia, R, Gkranias, N, et al. Mean annual attachment, bone level, and tooth loss: A systematic review. J Clin Periodontol. 2018; 45( Suppl 20): S112– S129. • O'Leary, T.J., Drake, R.B. and Naylor, J.E. (1972), The Plaque Control Record. Journal of Periodontology, 43: 38-38.
• Page RC, Schroeder HE. Pathogenesis of inflammatory periodontal disease. A summary of current work. Lab Invest. 1976;34(3):235-249. • Park OJ, Yi H, Jeon JH, et al. Pyrosequencing Analysis of Subgingival Microbiota in Distinct Periodontal Conditions. J Dent Res. 2015;94(7):921-927.
• Persson GR, Renvert S. Cluster of bacteria associated with peri-implantitis. Clin Implant Dent Relat Res. 2014;16(6):783-793.
• Pontoriero R, Tonelli MP, Carnevale G, Mombelli A, Nyman SR, Lang NP. Experimentally induced peri-implant mucositis. A clinical study in humans. Clin Oral Implants Res. 1994;5(4):254-259.
• Pulcini A, Bollaín J, Sanz-Sánchez I, et al. Clinical effects of the adjunctive use of a 0.03% chlorhexidine and 0.05% cetylpyridinium chloride mouth rinse in the management of peri-implant diseases: A randomized clinical trial. J Clin Periodontol. 2019;46(3):342-353.
• Quirynen M, Avontroodt P, Peeters W, Pauwels M, Coucke W, van Steenberghe D. Effect of different chlorhexidine formulations in mouthrinses on de novo plaque formation. J Clin Periodontol. 2001;28(12):1127-1136.
• Rakic M, Galindo-Moreno P, Monje A, et al. How frequent does peri-implantitis occur? A systematic review and meta-analysis. Clin Oral Investig. 2018;22(4):1805-1816.
• Ramberg P, Lindhe J, Botticelli D, Botticelli A. The effect of a triclosan dentifrice on mucositis in subjects with dental implants: a six-month clinical study. J Clin Dent. 2009;20(3):103-107.
• Rodrigo D, Martin C, Sanz M. Biological complications and peri-implant clinical and radiographic changes at immediately placed dental implants. A prospective 5-year cohort study. Clin Oral Implants Res. 2012;23(10):1224-1231.
• Rodrigo D, Sanz-Sánchez I, Figuero E, et al. Prevalence and risk indicators of peri-implant diseases in Spain. J Clin Periodontol. 2018;45(12):1510-1520.
• Roos-Jansåker AM, Lindahl C, Renvert H, Renvert S. Nine- to fourteen-year follow-up of implant treatment. Part I: implant loss and associations to various factors. J Clin Periodontol. 2006;33(4):283-289.
• Roos-Jansåker AM, Lindahl C, Renvert H, Renvert S. Nine- to fourteen-year follow-up of implant treatment. Part II: presence of peri-implant lesions. J Clin Periodontol. 2006;33(4):290-295.
• Roos-Jansåker AM, Renvert H, Lindahl C, Renvert S. Nine- to fourteen-year follow-up of implant treatment. Part III: factors associated with peri-implant lesions. J Clin Periodontol. 2006;33(4):296-301.
• Salvi, G.E., Aglietta, M., Eick, S., Sculean, A., Lang, N.P. and Ramseier, C.A. (2012), Reversibility of experimental peri‐implant mucositis compared with experimental gingivitis in humans. Clinical Oral Implants Research, 23: 182-190.
• Sanz M, van Winkelhoff AJ, Herrera D, Dellemijn-Kippuw N, Simón R, Winkel E. Differences in the composition of the subgingival microbiota of two periodontitis populations of different geographical origin. A comparison between Spain and The Netherlands. Eur J Oral Sci. 2000;108(5):383-392.
• Sanz‐Sánchez, I, Sanz‐Martín, I, Carrillo de Albornoz, A, Figuero, E, Sanz, M. Biological effect of the abutment material on the stability of peri‐implant marginal bone levels: A systematic review and meta‐analysis. Clin Oral Impl Res. 2018; (Suppl. 18): 124– 144.
• Serrano J, Escribano M, Roldán S, Martín C, Herrera D. Efficacy of adjunctive anti-plaque chemical agents in managing gingivitis: a systematic review and meta-analysis. J Clin Periodontol. 2015;42 Suppl 16:S106-S138.
• Schwarz F, Becker K, Sager M. Efficacy of professionally administered plaque removal with or without adjunctive measures for the treatment of peri-implant mucositis. A systematic review and meta-analysis. J Clin Periodontol. 2015;42 Suppl 16:S202-S213.
• Schwarz F, Derks J, Monje A, Wang HL. Peri-implantitis. J Clin Periodontol. 2018;45 Suppl 20:S246-S266.
• Shapiro S, Giertsen E, Guggenheim B. An in vitro oral biofilm model for comparing the efficacy of antimicrobial mouthrinses. Caries Res. 2002;36(2):93100.
• Shaw L, Harjunmaa U, Doyle R, et al. Distinguishing the Signals of Gingivitis and Periodontitis in Supragingival Plaque: a Cross-Sectional Cohort Study in Malawi. Appl Environ Microbiol. 2016;82(19):6057-6067. Published 2016 Sep 16.
• Tonetti MS, Chapple IL, Jepsen S, Sanz M. Primary and secondary prevention of periodontal and peri-implant diseases: Introduction to, and objectives of the 11th European Workshop on Periodontology consensus conference. J Clin Periodontol. 2015;42 Suppl 16:S1-S4.
• Tonetti, M.S., Gerber, L. and Lang, N.P. (1994), Vascular adhesion molecules and initial development of inflammation in clinically healthy human keratinized mucosa around teeth and osseointegrated implants. Journal of Periodontal Research, 29: 386-392.
• Tonetti, MS, Greenwell, H, Kornman, KS. Staging and grading of periodontitis: Framework and proposal of a new classification and case definition. J Periodontol. 2018; 89( Suppl 1): S159– S172.
• Tonetti MS, Imboden M, Gerber L, Lang NP. Compartmentalization of inflammatory cell phenotypes in normal gingiva and peri-implant keratinized mucosa. J Clin Periodontol. 1995;22(10):735-742.
• Trombelli, L, Farina, R, Silva, CO, Tatakis, DN. Plaque‐induced gingivitis: Case definition and diagnostic considerations. J Clin Periodontol. 2018; 45( Suppl 20): S44– S67.
• Trombelli L, Tatakis DN, Scapoli C, Bottega S, Orlandini E, Tosi M. Modulation of clinical expression of plaque-induced gingivitis. II. Identification of "highresponder" and "low-responder" subjects. J Clin Periodontol. 2004;31(4):239252.
• U.S. Public Health Service NCHS. Periodontal Disease in Adults, United States 1960–1962. PHS Publ. No. 1000. Vol. Series 11 No. 12. Washington, DC: Government Printing Office; 1965.
• Van Strydonck DA, Slot DE, Van der Velden U, Van der Weijden F. Effect of a chlorhexidine mouthrinse on plaque, gingival inflammation and staining in gingivitis patients: a systematic review. J Clin Periodontol. 2012;39(11):10421055.
• White DA, Tsakos G, Pitts NB, et al. Adult Dental Health Survey 2009: common oral health conditions and their impact on the population. Br Dent J. 2012;213(11):567-572.
• Zeza B, Farina R, Pilloni A, Mongardini C. Clinical outcomes of experimental gingivitis and peri-implant mucositis treatment with professionally administered plaque removal and photodynamic therapy. Int J Dent Hyg. 2018;16(2):e58-e64.
Zitzmann NU, Abrahamsson I, Berglundh T, Lindhe J. Soft tissue reactions to plaque formation at implant abutments with different surface topography. An experimental study in dogs. J Clin Periodontol. 2002;29(5):456-461.
• Zitzmann NU, Berglundh T, Marinello CP, Lindhe J. Experimental peri-implant mucositis in man. J Clin Periodontol. 2001;28(6):517-523.