Publication:
Prevalencia e indicadores de protección y riesgo de las enfermedades periimplantarias. Un estudio transversal de pacientes del master de Periodoncia de la Universidad Complutense de Madrid.

Loading...
Thumbnail Image
Official URL
Full text at PDC
Publication Date
2020
Advisors (or tutors)
Editors
Journal Title
Journal ISSN
Volume Title
Publisher
Citations
Google Scholar
Research Projects
Organizational Units
Journal Issue
Abstract
Objetivo. Evaluar la prevalencia de enfermedades periimplantarias e identificar indicadores de riesgo / protección para la periimplantitis. Materiales y métodos. Se invitaron a participar a 240 pacientes seleccionados al azar de una base de datos de clínicas universitarias. Aquellos que aceptaron, una vez que se recopilaron los datos de su historial médico y dental, fueron examinados clínica y radiográficamente para evaluar la prevalencia de salud y las enfermedades periimplantarias. Se realizó un análisis de regresión logística multivariante multinivel para identificar aquellos factores asociados, ya sea de manera directa (riesgo) o inversa (protectora) con la periimplantitis, definida como nivel óseo marginal ≧ 2 mm y sangrado al sondaje (SaS) /supuración (Sup). Resultados Se analizaron 99 pacientes con un total de 458 implantes dentales. La prevalencia de preperiimplantitis y periimplantitis a nivel del paciente fue del 56,6% y 31,3%. Los siguientes factores se identificaron como indicadores de riesgo de periimplantitis: tabaquismo (OR = 3.59; IC del 95%: 1.528.45), periodontitis moderada / avanzada (OR = 2.77; IC del 95%: 1.20-6.36), <16 dientes remanentes (OR = 2.23; IC 95%: 1.05-4.73). También, se identificaron los siguientes factores como indicadores de protección: uso de hilo dental / cepillado interproximal (OR = 0.27; IC 95%: 0.11-0.68), inhibidores de la bomba de protones (OR = 0.08; IC 95%: 0.01-0.90) y anticoagulantes (OR = 0,08; IC del 95%: 0,01-0,56). Conclusiones Las enfermedades periimplantarias son altamente prevalentes entre los pacientes con implantes dentales en esta población universitaria. Se identificaron varios factores como indicadores de riesgo y de protección de la periimplantitis.
Aim. To evaluate the prevalence of peri-implant diseases and to identify risk/protective indicators of peri-implantitis. Materials and Methods. 240 randomly selected patients from a university clinic database were invited to participate. Those who accepted, once data from their medical and dental history was collected, were examined clinically and radiographically to assess the prevalence of peri-implant health and diseases. A multilevel multivariate logistic regression analysis was carried out to identify those factors associated either directly (risk) or indirectly (protective) with peri-implantitis defined as bone levels ≧2 mm and BoP/SoP. Results. 99 patients with a total of 458 dental implants were analyzed. The prevalence of preperiimplantitis and of peri-implantitis were respectively 56.6% and 31.3% at patient-level. The following factors were identified as risk indicators for peri-implantitis: smoking (OR=3.59; 95%CI:1.52-8.45), moderate/severe periodontitis (OR=2.77; 95%CI:1.20-6.36), <16 remaining teeth (OR=2.23; 95%CI:1.05-4.73). Conversely, the following factors were identified as protective indicators: interproximal flossing/brushing (OR=0.27; 95%CI:0.11-0.68), proton pump inhibitors (OR=0.08; 95%CI:0.01-0.90) and anticoagulants (OR=0.08; 95%CI:0.01-0.56). Conclusions. Peri-implant diseases are highly prevalent among patients with dental implants in this university-based population. Several factors were identified as risk- and protective-indicators of periimplantitis
Description
Trabajo Fin de Master encuadrado en la línea de investigación Etiología y patogenia de las enfermedades periodotnales y periimplantarias.
Keywords
Citation
American Academy of Sleep Medicine (AASM): In (eds): International classification of sleep disorders. Diagnosis and coding manual. (ICSD-2). Section on sleep related bruxism, 2nd edition. Westchester (IL): American Academy of Sleep Medicine, 2005. pp. 189-192. Amerio, E., Mainas, G., Petrova, D., Giner Tarrida, L., Nart, J., & Monje, A. (2020). Compliance with supportive periodontal/peri- implant therapy: A systematic review. J Clin Periodontol, 47(1), 81–100. http://doi.org/10.1111/jcpe.13204 Barootchi, S., Ravidà, A., Tavelli, L., & Wang, H.-L. (2020). Nonsurgical treatment for peri-implant mucositis: A systematic review and meta-analysis. International Journal of Oral Implantology (New Malden, London, England), 13(2), 123–139. Berglundh, T., Armitage, G., Araujo, M. G., Avila-Ortiz, G., Blanco, J., Camargo, P. M., et al. (2018a). Peri-implant diseases and conditions: Consensus report of workgroup 4 of the 2017 World Workshop on the Classification of Periodontal and Peri- Implant Diseases and Conditions, 45(Suppl 20), S286– S291. http://doi.org/10.1111/jcpe.12957 Berglundh, T., Wennström, J. L., & Lindhe, J. (2018b). Long-term outcome of surgical treatment of peri-implantitis. A 2-11-year retrospective study. Clinical Oral Implants Research, 29(4), 404–410. Carcuac, O., Derks, J., Abrahamsson, I., Wennström, J. L., Petzold, M., & Berglundh, T. (2017). Surgical treatment of peri- implantitis: 3-year results from a randomized controlled clinical trial. J Clin Periodontol, 44(12), 1294–1303. http://doi.org/10.1111/jcpe.12813 Carra, M. C., Huynh, N., & Lavigne, G. (2012). Sleep bruxism: a comprehensive overview for the dental clinician interested in sleep medicine. Dent Clin North Am, 56(2), 387–413. http://doi.org/10.1016/j.cden.2012.01.003 Cha, J. K., Lee, J. S., & Kim, C. S. (2019). Surgical Therapy of Peri-Implantitis with Local Minocycline: A 6-Month Randomized Controlled Clinical Trial. J Dent Res, 98(3), 288–295. http://doi.org/10.1177/0022034518818479 Chappuis, V., Avila-Ortiz, G., Araujo, M. G., & Monje, A. (2018). Medication-related dental implant failure: Systematic review and meta-analysis. Clinical Oral Implants Research, 29 Suppl 16, 55–68. http://doi.org/10.1111/clr.13137 Costa, F. O., Takenaka-Martinez, S., Cota, L. O. M., Ferreira, S. D., Silva, G. L. M., & Costa, J. E. (2012). Peri-implant disease in subjects with and without preventive maintenance: a 5-year follow-up. J Clin Periodontol, 39(2), 173–181. http://doi.org/10.1111/j.1600-051X.2011.01819.x Dalago, H. R., Schuldt Filho, G., Rodrigues, M. A. P., Renvert, S., & Bianchini, M. A. (2017). Risk indicators for Peri-implantitis. A cross-sectional study with 916 implants. Clinical Oral Implants Research, 28(2), 144–150. http://doi.org/10.1111/clr.12772 de Tapia, B., Valles, C., Ribeiro-Amaral, T., Mor, C., Herrera, D., Sanz, M., & Nart, J. (2019). The adjunctive effect of a titanium brush in implant surface decontamination at peri-implantitis surgical regenerative interventions: A randomized controlled clinical trial. J Clin Periodontol, 46(5), 586–596. http://doi.org/10.1111/jcpe.13095 Derks, J., & Tomasi, C. (2015). Peri-implant health and disease. A systematic review of current epidemiology. J Clin Periodontol, 42 Suppl 16, S158–71. http://doi.org/10.1111/jcpe.12334 Derks, J., Schaller, D., Hakansson, J., Wennstrom, J. L., Tomasi, C., & Berglundh, T. (2016a). Effectiveness of Implant Therapy Analyzed in a Swedish Population: Prevalence of Peri-implantitis. J Dent Res, 95(1), 43–49. http://doi.org/10.1177/0022034515608832 Derks, J., Schaller, D., Håkansson, J., Wennström, J. L., Tomasi, C., & Berglundh, T. (2016b). Periimplantitis - onset and pattern of progression. J Clin Periodontol, 43(4), 383–388. http://doi.org/10.1111/jcpe.12535 Eke, P. I., Page, R. C., Wei, L., Thornton-Evans, G., & Genco, R. J. (2012). Update of the case definitions for population-based surveillance of periodontitis. J Periodontol, 83(12), 1449–1454. Elm, von, E., Altman, D. G., Egger, M., Pocock, S. J., Gotzsche, P. C., & Vandenbroucke, J. P. (2007). The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Lancet, 370(9596), 1453–1457. http://doi.org/10.1016/S0140-6736(07)61602-X Ferreira, S. D., Silva, G. L. M., Cortelli, J. R., Costa, J. E., & Costa, F. O. (2006). Prevalence and risk variables for peri-implant disease in Brazilian subjects. J Clin Periodontol, 33(12), 929–935. http://doi.org/10.1111/j.1600-051X.2006.01001.x Figuero, E., Graziani, F., Sanz, I., Herrera, D., & Sanz, M. (2014). Management of peri-implant mucositis and peri-implantitis. Periodontol 2000, 66(1), 255–273. http://doi.org/10.1111/prd.12049 Flores-Guillen, J., Álvarez-Novoa, C., Barbieri, G., Martin, C., & Sanz, M. (2018). Five-year outcomes of a randomized clinical trial comparing bone-level implants with either submerged or transmucosal healing. J Clin Periodontol, 45(1), 125–135. http://doi.org/10.1111/jcpe.12832 Fransson, C., Wennström, J., Tomasi, C., & Berglundh, T. (2009). Extent of peri-implantitis-associated bone loss. J Clin Periodontol, 36(4), 357–363. http://doi.org/10.1111/j.1600-051X.2009.01375.x Heitz-Mayfield, L. J. A., & Salvi, G. E. (2018). Peri-implant mucositis. J Clin Periodontol, 45 Suppl 20, S237–S245. http://doi.org/10.1111/jcpe.12953 Heitz-Mayfield, L. J. A., Heitz, F., & Lang, N. P. (2020). Implant Disease Risk Assessment IDRA-a tool for preventing peri-implant disease. Clinical Oral Implants Research, 31(4), 397–403. http://doi.org/10.1111/clr.13585 Heitz-Mayfield, L. J. A., Salvi, G. E., Mombelli, A., Loup, P.-J., Heitz, F., Kruger, E., & Lang, N. P. (2018). Supportive peri-implant therapy following anti-infective surgical peri-implantitis treatment: 5year survival and success. Clinical Oral Implants Research, 29(1), 1–6. http://doi.org/10.1111/clr.12910 Jepsen, S., Berglundh, T., Genco, R., Aass, A. M., Demirel, K., Derks, J., et al. (2015). Primary prevention of peri-implantitis: managing peri-implant mucositis. J Clin Periodontol, 42 Suppl 16, S152–7. http://doi.org/10.1111/jcpe.12369 Katafuchi, M., Weinstein, B. F., Leroux, B. G., Chen, Y.-W., & Daubert, D. M. (2018). Restoration contour is a risk indicator for peri-implantitis: A cross-sectional radiographic analysis. J Clin Periodontol, 45(2), 225–232. http://doi.org/10.1111/jcpe.12829 Kedika, R. R., Souza, R. F., & Spechler, S. J. (2009). Potential anti-inflammatory effects of proton pump inhibitors: a review and discussion of the clinical implications. Digestive Diseases and Sciences, 54(11), 2312–2317. http://doi.org/10.1007/s10620- 009-0951-9 Kordbacheh Changi, K., Finkelstein, J., & Papapanou, P. N. (2019). Peri-implantitis prevalence, incidence rate, and risk factors: A study of electronic health records at a U.S. dental school. Clinical Oral Implants Research, 30(4), 306–314. http://doi.org/10.1111/clr.13416 Mir-Mari, J., Mir-Orfila, P., Figueiredo, R., Valmaseda-Castellón, E., & Gay-Escoda, C. (2012). Prevalence of peri-implant diseases. A cross-sectional study based on a private practice environment. J Clin Periodontol, 39(5), 490–494. http://doi.org/10.1111/j.1600-051X.2012.01872.x Monje, A., & Blasi, G. (2019). Significance of keratinized mucosa/gingiva on peri-implant and adjacent periodontal conditions in erratic maintenance compliers. J Periodontol, 90(5), 445–453. http://doi.org/10.1002/JPER.18-0471 Monje, A., Aranda, L., Diaz, K. T., Alarcón, M. A., Bagramian, R. A., Wang, H. L., & Catena, A. (2016). Impact of Maintenance Therapy for the Prevention of Peri-implant Diseases: A Systematic Review and Meta-analysis. J Dent Res, 95(4), 372–379. http://doi.org/10.1177/0022034515622432 Monje, A., Wang, H.-L., & Nart, J. (2017). Association of Preventive Maintenance Therapy Compliance and Peri-Implant Diseases: A Cross-Sectional Study. J Periodontol, 88(10), 1030–1041. http://doi.org/10.1902/jop.2017.170135 Müller, K. A. L., Chatterjee, M., Rath, D., & Geisler, T. (2015). Platelets, inflammation and antiinflammatory effects of antiplatelet drugs in ACS and CAD. Thrombosis and Haemostasis, 114(3), 498–518. http://doi.org/10.1160/TH14-11-0947 Nart, J., Pons, R., Valles, C., Esmatges, A., Sanz-Martín, I., & Monje, A. (2020). Non-surgical therapeutic outcomes of peri- implantitis: 12-month results. Clinical Oral Investigations, 24(2), 675– 682. http://doi.org/10.1007/s00784-019-02943-8 Pimentel, S. P., Shiota, R., Cirano, F. R., Casarin, R. C. V., Pecorari, V. G. A., Casati, M. Z., et al. (2018). Occurrence of peri- implant diseases and risk indicators at the patient and implant levels: A multilevel cross-sectional study. J Periodontol, 89(9), 1091–1100. http://doi.org/10.1002/JPER.170599 Rakic, M., Galindo Moreno, P., Monje, A., Radovanovic, S., Wang, H.-L., Cochran, D., et al. (2018). How frequent does peri- implantitis occur? A systematic review and meta-analysis. Clinical Oral Investigations, 22(4), 1805–1816. http://doi.org/10.1007/s00784-017-2276-y Ravidà, A., Galli, M., Siqueira, R., Saleh, M. H. A., Galindo Moreno, P., & Wang, H.-L. (2020a). Diagnosis of peri-implant status after peri-implantitis treatment: Proposal of a new classification. J Periodontol. http://doi.org/10.1002/JPER.20-0124 Ravidà, A., Saleh, I., Siqueira, R., Garaicoa-Pazmiño, C., Saleh, M. H. A., Monje, A., & Wang, H.-L. (2020b). Influence of keratinized mucosa on the surgical therapeutical outcomes of peri-implantitis. J Clin Periodontol, 47(4), 529–539. http://doi.org/10.1111/jcpe.13250 Renvert, S., Persson, G. R., Pirih, F. Q., & Camargo, P. M. (2018). Peri-implant health, peri-implant mucositis, and peri-implantitis: Case definitions and diagnostic considerations, 45(Suppl 20), S278– S285. http://doi.org/10.1111/jcpe.12956 Roccuzzo, M., Layton, D. M., Roccuzzo, A., & Heitz-Mayfield, L. J. (2018). Clinical outcomes of peri-implantitis treatment and supportive care: A systematic review. Clinical Oral Implants Research, 29 Suppl 16, 331–350. http://doi.org/10.1111/clr.13287 Rodrigo, D., Sanz-Sanchez, I., Figuero, E., Llodra, J. C., Bravo, M., Caffesse, R. G., et al. (2018). Prevalence and risk indicators of peri-implant diseases in Spain. J Clin Periodontol, 45(12), 1510– 1520. http://doi.org/10.1111/jcpe.13017 Romandini, M., Cordaro, M., Donno, S., & Cordaro, L. (2019). Discrepancy between patient satisfaction and biologic complication rate in patients rehabilitated with overdentures and not participating in a structured maintenance program after 7 to 12 years of loading. The International Journal of Oral & Maxillofacial Implants, 34(5), 1143–1151. http://doi.org/10.11607/jomi.7465 Roos-Jansaker, A.-M., Renvert, H., Lindahl, C., & Renvert, S. (2006). Nine- to fourteen-year followup of implant treatment. Part III: factors associated with peri-implant lesions. J Clin Periodontol, 33(4), 296–301. http://doi.org/10.1111/j.1600- 051X.2006.00908.x Sanz, M., & Chapple, I. L. (2012). Clinical research on peri-implant diseases: consensus report of Working Group 4. J Clin Periodontol, 39 Suppl 12, 202–206. http://doi.org/10.1111/j.1600051X.2011.01837.x Sanz-Martín, I., Regidor, E., Navarro, J., Sanz-Sanchez, I., Sanz, M., & Ortiz-Vigon, A. (2020). Factors associated with the presence of peri-implant buccal soft tissue dehiscences: A case-control study. J Periodontol. http://doi.org/10.1002/JPER.19-0490 Schwarz, F., Derks, J., Monje, A., & Wang, H.-L. (2018). Peri-implantitis. J Clin Periodontol, 45 Suppl 20, S246–S266. http://doi.org/10.1111/jcpe.12954 Staubli, N., Walter, C., Schmidt, J. C., Weiger, R., & Zitzmann, N. U. (2017). Excess cement and the risk of peri-implant disease - a systematic review. Clinical Oral Implants Research, 28(10), 1278– 1290. http://doi.org/10.1111/clr.12954 Tomasi, C., & Derks, J. (2012). Clinical research of peri-implant diseases--quality of reporting, case definitions and methods to study incidence, prevalence and risk factors of peri-implant diseases. J Clin Periodontol, 39 Suppl 12, 207–223. http://doi.org/10.1111/j.1600-051X.2011.01831.x Vandenbroucke, J. P., Elm, von, E., Altman, D. G., Gotzsche, P. C., Mulrow, C. D., Pocock, S. J., et al. (2007). Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): explanation and elaboration. Epidemiology (Cambridge, Mass.), 18(6), 805–835. Vignoletti, F., Di Domenico, G. L., Di Martino, M., Montero, E., & De Sanctis, M. (2019). Prevalence and risk indicators of peri- implantitis in a sample of university-based dental patients in Italy: A crosssectional study. J Clin Periodontol, 46(5), 597–605. http://doi.org/10.1111/jcpe.13111 Wada, M., Mameno, T., Onodera, Y., Matsuda, H., Daimon, K., & Ikebe, K. (2019). Prevalence of peri-implant disease and risk indicators in a Japanese population with at least 3 years in function-A multicentre retrospective study. Clinical Oral Implants Research, 30(2), 111–120. http://doi.org/10.1111/clr.13397