Publication: Cirugía de ojo seco y cataratas
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2021-02-16
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Universidad Complutense de Madrid
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Abstract
La cirugía de cataratas , uno de los procedimientos quirúrgicos realizados con más frecuencia en el mundo, es segura y eficaz. Sin embargo, este tipo de cirugía es un factor de riesgo para la enfermedad del ojo seco que puede conllevar a una insatisfacción con el resultado postquirúrgico y puede afectar negativamente a la calidad de vida del paciente. En la presente tesis se ha utilizado un modelo in vitro para explorar los posibles factores por los cuales la cirugía oftálmica podría impactar en la superficie ocular y, a su vez, conducir a signos y síntomas postquirúrgicos que son característicos del ojo seco. Estos incluyeron la exposición a la luz del microscopio quirúrgico y el uso de agentes antisépticos tales como la povidona yodada...
Cataract surgery, one of the most frequently performed surgical procedures in the world, is safe and efficacious, however, it is a risk factor for dry eye disease which can lead to dissatisfaction with the outcome and can adversely impact quality of life. This thesis explores possible mechanisms whereby ophthalmic surgery could impact on the ocular surface and, in turn, lead to dry eye signs and symptoms postoperatively. Contributing factors may include light from the operating microscope, disruption of ocular tissues and antiseptic agents used such as povidone iodine.This research attempted to understand the how cataract surgery affects the ocular surface by using an in vitro model. Porcine conjunctival fibroblasts were assessed after exposure to some of the stressors associated with surgery to observe the possible damage with three different approaches...
Cataract surgery, one of the most frequently performed surgical procedures in the world, is safe and efficacious, however, it is a risk factor for dry eye disease which can lead to dissatisfaction with the outcome and can adversely impact quality of life. This thesis explores possible mechanisms whereby ophthalmic surgery could impact on the ocular surface and, in turn, lead to dry eye signs and symptoms postoperatively. Contributing factors may include light from the operating microscope, disruption of ocular tissues and antiseptic agents used such as povidone iodine.This research attempted to understand the how cataract surgery affects the ocular surface by using an in vitro model. Porcine conjunctival fibroblasts were assessed after exposure to some of the stressors associated with surgery to observe the possible damage with three different approaches...
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Tesis inédita de la Universidad Complutense de Madrid, Facultad de Óptica y Optometría, leída el 28-11-2020