Publication: Efecto del cannabidiol y su interacción con la morfina sobre la concentración alveolar mínima del sevoflurano en rata
Loading...
Files
Official URL
Full text at PDC
Publication Date
2021-02-26
Authors
Advisors (or tutors)
Editors
Journal Title
Journal ISSN
Volume Title
Publisher
Universidad Complutense de Madrid
Citations
Exportar
Abstract
El cannabidiol (CBD) es un componente natural de la planta Cannabissativa, el cual, a diferencia de otros cannabinoides (como por ejemplo el Δ-9Tetrahydrocannabidiol (THC)) carece de efectos psicoactivos, aunque posee efecto analgésico y se ha demostrado también una potente acción antiinflamatoria e inmunomoduladora. Se sabe que la morfina reduce la concentración alveolarmínima del sevoflurano (CAMSEV) en rata en un 30%, sin embargo, los efectos del CBD en la CAMSEV no se han estudiado. Tampoco se ha investigado la posible interacción entre el CBD y la morfina sobre la CAMSEV. Este trabajo estudia el efecto del CBD sobre la reducción que produce la morfina en la CAM del sevoflurano en rata...
Cannabidiol (CBD) is a natural component of Cannabis sativa that,unlike others canabinoids (for example, Δ-9 Tetrahydrocannabidiol (THC)) is devoid of psychotomimetic activity, but produces antinocioceptive effects, and also demostrates potent antiinflamatory and inmunomodulatory actions. It is known that morphine produces a 30% reduction on sevoflurane minimum alveolar concentration (MACSEV) in the rat, but CBD effects on the MACSEV have not been studied. Nor, possible interaction between CBD and morphine on MACSEV has been investigated. The present study investigated the effect of CBD on sevoflurane MAC reduction in rats and the change in the effect when added morphine...
Cannabidiol (CBD) is a natural component of Cannabis sativa that,unlike others canabinoids (for example, Δ-9 Tetrahydrocannabidiol (THC)) is devoid of psychotomimetic activity, but produces antinocioceptive effects, and also demostrates potent antiinflamatory and inmunomodulatory actions. It is known that morphine produces a 30% reduction on sevoflurane minimum alveolar concentration (MACSEV) in the rat, but CBD effects on the MACSEV have not been studied. Nor, possible interaction between CBD and morphine on MACSEV has been investigated. The present study investigated the effect of CBD on sevoflurane MAC reduction in rats and the change in the effect when added morphine...
Description
Tesis inédita de la Universidad Complutense de Madrid, Facultad de Veterinaria, Departamento de Medicina y Cirugía Animal, leída el 03-03-2020