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Visual function, ocular surface integrity and symptomatology of a new extended depth-of-focus and a conventional multifocal contact lens

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Martínez Alberquilla, Irene and García Montero, María and Ruiz Alcocer, Javier and Crooke, Almudena and Madrid Costa, David (2020) Visual function, ocular surface integrity and symptomatology of a new extended depth-of-focus and a conventional multifocal contact lens. Contact Lens and Anterior Eye . 6 p.. ISSN 1367-0484 (In Press)

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Official URL: https://doi.org/10.1016/j.clae.2020.11.004



Abstract

Purpose: To evaluate visual function, ocular surface integrity and dry eye symptoms with an extended depth-of-focus (EDOF) design and a conventional multifocal (MF) contact lens (CL) after 15 days of wear.
Methods: A crossover single mask randomised clinical trial was conducted including 30 presbyopes who used an EDOF and a conventional MF CL (Biofinity MF) for 15 days each. Defocus curves, depth-of-focus range, contrast sensitivity (CS) under photopic and mesopic conditions (with and without glare) and subjective perception of halos and glare were evaluated. The ocular surface was evaluated through non-invasive Keratograph tear breakup time (NIKBUT), averaged tear breakup time (NIKBUT-avg), tear meniscus height (TMH), bulbar and limbal redness, and conjunctival and corneal staining. Dry eye symptoms were assessed with the OSDI questionnaire.
Results: No statistically significant differences were found for defocus curves or depth-of-focus between the two CLs (both p > 0.05). Subjective perception of halos and glare was not significantly different between CLs. Statistically significant differences were observed for CS under mesopic conditions for low spatial frequencies (p = 0.008). None of the CL produced significant changes in NIKBUT, NIKBUT-avg, TMH or redness. No change in conjunctival staining was observed in 76.7 % and 73.3 % of participants for EDOF and Biofinity MF, respectively. No change in corneal staining was observed in 86.7 % and 83.3 % of participants for EDOF and Biofinity MF, respectively. No changes were observed in the symptomatology measured with OSDI questionnaire (p > 0.05).
Conclusions: Both CL for presbyopia offer good visual quality, preserve the ocular surface integrity and provide the patient with similar symptomatology levels after 15 days of lens wear.


Item Type:Article
Additional Information:

Received 29 July 2020, Revised 9 November 2020, Accepted 10 November 2020, Available online 23 November 2020.

Uncontrolled Keywords:Extended depth-of-focus; Multifocal contact lens; Presbyopia
Subjects:Medical sciences > Optics > Contact lenses
Medical sciences > Optics > Optometry
ID Code:64214
Deposited On:03 Mar 2021 13:22
Last Modified:04 Mar 2021 08:26

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