Real-Time 3D PET Image with Pseudoinverse Reconstruction



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López Montes, Alejandro and Galve Lahoz, Pablo and Udías Moinelo, José Manuel and Cal-González, Jacobo and Vaquero, Juan José and Desco, Manuel and López Herraiz, Joaquín (2020) Real-Time 3D PET Image with Pseudoinverse Reconstruction. Applied Sciences, 10 (8). p. 2829. ISSN 2076-3417

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Real-time positron emission tomography (PET) may provide information from first-shot images, enable PET-guided biopsies, and allow awake animal studies. Fully-3D iterative reconstructions yield the best images in PET, but they are too slow for real-time imaging. Analytical methods such as Fourier back projection (FBP) are very fast, but yield images of poor quality with artifacts due to noise or data incompleteness. In this work, an image reconstruction based on the pseudoinverse of the system response matrix (SRM) is presented. w. To implement the pseudoinverse method, the reconstruction problem is separated into two stages. First, the axial part of the SRM is pseudo-inverted (PINV) to rebin the 3D data into 2D datasets. Then, the resulting 2D slices can be reconstructed with analytical methods or by applying the pseudoinverse algorithm again. The proposed two-step PINV reconstruction yielded good-quality images at a rate of several frames per second, compatible with real time applications. Furthermore, extremely fast direct PINV reconstruction of projections of the 3D image collapsed along specific directions can be implemented.

Item Type:Article
Uncontrolled Keywords:positron emission tomography; rebinning; real-time; image reconstruction; system matrix; pseudoinverse
Subjects:Sciences > Physics > Materials
ID Code:65364
Deposited On:07 May 2021 16:31
Last Modified:10 May 2021 06:58

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