Partial Genetic Turnover in Neandertals: Continuity in the East and Population Replacement in the West

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Dalén, L. and Orlando, Ludovic and Shapiro, Beth and Brandström-Durling, Mikael and Quam, Rolf and Thomas P. Gilbert, M. and Díez Fernández-Lomana, Juan Carlos and Willerslev, Eske and Arsuaga, Juan Luis and Götherström, Anders (2012) Partial Genetic Turnover in Neandertals: Continuity in the East and Population Replacement in the West. Molecular Biology and Evolution, 29 (8). pp. 1893-1897. ISSN 1537-1719

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Abstract

Remarkably little is known about the population-level processes leading up to the extinction of the neandertal. To examine this, we use mitochondrial DNA sequences from 13 neandertal individuals, including a novel sequence from northern Spain, to examine neandertal demographic history. Our analyses indicate that recent western European neandertals (<48 kyr) constitute a tightly defined group with low mitochondrial genetic variation in comparison with both eastern and older (>48 kyr) European neandertals. Using control region sequences, Bayesian demographic simulations provide higher support for a model of population fragmentation followed by separate demographic trajectories in subpopulations over a null model of a single stable population. The most parsimonious explanation for these results is that of a population turnover in western Europe during early Marine Isotope Stage 3, predating the arrival of anatomically modern humans in the region.


Item Type:Article
Uncontrolled Keywords:Neanderthal; demography; climate change; ancient DNA.
Subjects:Sciences > Geology > Paleontology
Medical sciences > Biology > Molecular biology
ID Code:65454
Deposited On:14 May 2021 06:08
Last Modified:19 May 2021 14:18

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