An Early, Universal Mediterranean Diet-Based Intervention in Pregnancy Reduces Cardiovascular Risk Factors in the “Fourth Trimester”



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Assaf Balut, Carla and Garcia de la Torre, Nuria and Durán Rodríguez-Hervada, Alejandra and Bordiú, Elena and Valle, Laura del and Familiar, Cristina and Valerio, Johanna and Jimenez, Inés and Herraiz Martínez, Miguel Ángel and Izquierdo Méndez, Nuria and Runkle de la Vega, Isabelle and Miguel Novoa, María de la Paz de and Montañez, Carmen and Barabash, Ana and Cuesta, Martín and Rubio Herrera, Miguel Ángel and Calle Pascual, Alfonso Luis (2019) An Early, Universal Mediterranean Diet-Based Intervention in Pregnancy Reduces Cardiovascular Risk Factors in the “Fourth Trimester”. Journal of Clinical Medicine, 8 (9). p. 1499. ISSN 2077-0383

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An early antenatal dietary intervention could play an important role in the prevention of metabolic diseases postpartum. The aim of this study is to evaluate whether an early, specific dietary intervention reduces women’s cardiovascular risk in the “fourth trimester”. This prospective cohort study compares 1675 women from the standard-care group (ScG/n = 676), who received standard-care dietary guidelines, with the intervention group (IG/n = 999), who received Mediterranean diet (MedDiet)-based dietary guidelines, supplemented with extra-virgin olive oil and nuts. Cardiovascular risk was determined by the presence of metabolic syndrome (MetS) and insulin resistance syndrome (IrS) (HOMA-IR 3.5) at 12–14 weeks postpartum. MetS was less frequent in the IG (11.3 vs. 19.3%, p < 0.05). The intervention was associated with a reduction in the relative risk of having MetS: 0.74 (95% CI, 0.60–0.90), but not in the risk of IrS. When analyzing the presence of having one or more components of the MetS, the IG had significantly higher rates of having 0 components and lower rates of having ≥1 (p-trend = 0.029). An early MedDiet-based nutritional intervention in pregnancy is associated with reductions in postpartum rates of MetS.

Item Type:Article
Uncontrolled Keywords:Mediterranean diet; pregnancy; metabolic syndrome; postpartum
Subjects:Medical sciences > Medicine > Dietetics and Nutrition
Medical sciences > Medicine > Gynecology and Obstetrics
ID Code:65887
Deposited On:08 Jun 2021 15:52
Last Modified:09 Jun 2021 09:13

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