Dietary Polyphenol Intake is Associated with HDL-Cholesterol and A Better Profile of other Components of the Metabolic Syndrome: A PREDIMED-Plus Sub-Study



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Castro-Barquero, Sara and Tresserra-Rimbau, Anna and Vitelli-Storelli, Facundo and Doménech, Mónica and Salas-Salvadó, Jordi and Martín-Sánchez, Vicente and Rubín-García, María and Buil-Cosiales, Pilar and Corella, Dolores and Fitó, Montserrat and Romaguera, Dora and Vioque, Jesús and Alonso-Gómez, Ángel María and Wärnberg, Julia and Martínez, José Alfredo and Serra-Majem, Luís and Tinahones, Francisco José and Lapetra, José and Pintó, Xavier and Tur, Josep Antonio and Garcia-Rios, Antonio and García-Molina, Laura and Delgado-Rodriguez, Miguel and Matía Martín, Pilar and Daimiel, Lidia and Vidal, Josep and Vázquez, Clotilde and Cofán, Montserrat and Romanos-Nanclares, Andrea and Becerra-Tomas, Nerea and Barragan, Rocio and Castañer, Olga and Konieczna, Jadwiga and González-Palacios, Sandra and Sorto-Sánchez, Carolina and Pérez-López, Jessica and Zulet, María Angeles and Bautista-Castaño, Inmaculada and Casas, Rosa and Gómez-Perez, Ana María and Santos-Lozano, José Manuel and Rodríguez-Sanchez, María Ángeles and Julibert, Alicia and Martín-Calvo, Nerea and Hernández-Alonso, Pablo and Sorlí, José V and Sanllorente, Albert and Galmés-Panadés, Aina María and Cases-Pérez, Eugenio and Goicolea-Güemez, Leire and Ruiz-Canela, Miguel and Babio, Nancy and Hernáez, Álvaro and Lamuela-Raventós, Rosa María and Estruch, Ramon (2020) Dietary Polyphenol Intake is Associated with HDL-Cholesterol and A Better Profile of other Components of the Metabolic Syndrome: A PREDIMED-Plus Sub-Study. Nutrients, 12 (3). p. 689. ISSN 2072-6643

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Dietary polyphenol intake is associated with improvement of metabolic disturbances. The aims of the present study are to describe dietary polyphenol intake in a population with metabolic syndrome (MetS) and to examine the association between polyphenol intake and the components of MetS. This cross-sectional analysis involved 6633 men and women included in the PREDIMED (PREvención con DIeta MEDiterranea-Plus) study. The polyphenol content of foods was estimated from the Phenol-Explorer 3.6 database. The mean of total polyphenol intake was 846 ± 318 mg/day. Except for stilbenes, women had higher polyphenol intake than men. Total polyphenol intake was higher in older participants (>70 years of age) compared to their younger counterparts. Participants with body mass index (BMI) >35 kg/m2 reported lower total polyphenol, flavonoid, and stilbene intake than those with lower BMI. Total polyphenol intake was not associated with a better profile concerning MetS components, except for high-density lipoprotein cholesterol (HDL-c), although stilbenes, lignans, and other polyphenols showed an inverse association with blood pressure, fasting plasma glucose, and triglycerides. A direct association with HDL-c was found for all subclasses except lignans and phenolic acids. To conclude, in participants with MetS, higher intake of several polyphenol subclasses was associated with a better profile of MetS components, especially HDL-c.

Item Type:Article
Uncontrolled Keywords:polyphenols; metabolic syndrome; Mediterranean diet; glignans; stilbenes; HDL-cholesterol
Subjects:Medical sciences > Medicine > Dietetics and Nutrition
ID Code:66340
Deposited On:23 Jun 2021 10:41
Last Modified:23 Jun 2021 10:49

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