Dendrimers as Soft Nanomaterials for Electrochemical Immunosensors

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Sánchez Sánchez, Alfredo and Villalonga, Anabel and Martínez García, Gonzalo and Parrado Quintela, Concepción and Villalonga Santana, Reynaldo (2019) Dendrimers as Soft Nanomaterials for Electrochemical Immunosensors. Nanomaterials, 9 (12). p. 1745. ISSN 2079-4991

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Official URL: https://doi.org/10.3390/nano9121745




Abstract

Electrochemical immunosensors are antibody-based affinity biosensors with a high impact on clinical, environmental, food, and pharmaceutical analysis. In general, the analytical performance of these devices is critically determined by the materials and reagents used for their construction, signal production and amplification. Dendrimers are monodisperse and highly branched polymers with three-dimensional structures widely employed as “soft” nanomaterials in electrochemical immunosensor technology. This review provides an overview on the state-of-the-art in dendrimer-based electrochemical immunosensors, focusing on those using polyamidoamine and poly (propylene imine) dendrimers. Special emphasis is given to the most original methods recently reported for the construction of immunosensor architectures incorporating dendrimers, as well as to novel sensing approaches based on dendrimer-assisted signal enhancement strategies.


Item Type:Article
Uncontrolled Keywords:antibody; dendrimer; electrochemical immunosensor; polyamidoamine; poly (propylene imine)
Subjects:Sciences > Chemistry > Analytic chemistry
ID Code:66767
Deposited On:14 Jul 2021 14:22
Last Modified:15 Jul 2021 06:38

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