Strontium Ions Substitution in Brushite Crystals: The Role of Strontium Chloride

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Alkhraisat, Mohammad H. and Rueda, Carmen and López Cabarcos, Enrique (2011) Strontium Ions Substitution in Brushite Crystals: The Role of Strontium Chloride. Journal of Functional Biomaterials, 2 (2). pp. 31-38. ISSN 2079-4983

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Official URL: https://doi.org/10.3390/jfb2020031




Abstract

The incorporation of strontium chloride to brushite cement was successful to introduce strontium ions within the lattice of brushite crystals. The effect of strontium ions on brushite cement properties was concentration dependent; such that, the addition of 5% and 10% (w/w) SrCl2 significantly increased the cement FST and the addition of 10% SrCl2 decreased the cement tensile strength. Further, cement weight loss was shown to be increased by cement modification with SrCl2. The combination of ionic substitution and the degradability of brushite cements would constitute a system for the local delivery of strontium ions in the treatment of osteoporosis.


Item Type:Article
Uncontrolled Keywords:Brushite; calcium phosphate cement; strontium; glycolic acid
Subjects:Medical sciences > Pharmacy > Pharmaceutical chemistry
Medical sciences > Pharmacy > Physical chemistry
ID Code:67485
Deposited On:24 Aug 2021 10:06
Last Modified:06 Sep 2021 09:23

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