Caloric Restriction as a Strategy to Improve Vascular Dysfunction in Metabolic Disorders

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García Prieto, Concha and Fernández Alfonso, María Soledad (2016) Caloric Restriction as a Strategy to Improve Vascular Dysfunction in Metabolic Disorders. Nutrients, 8 (6). p. 370. ISSN 2072-6643

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Official URL: https://doi.org/10.3390/nu8060370




Abstract

Caloric restriction (CR) has proved to be the most effective and reproducible dietary intervention to increase healthy lifespan and aging. A reduction in cardiovascular disease (CVD) risk in obese subjects can be already achieved by a moderate and sustainable weight loss. Since pharmacological approaches for body weight reduction have, at present, a poor long-term efficacy, CR is of great interest in the prevention and/or reduction of CVD associated with obesity. Other dietary strategies changing specific macronutrients, such as altering carbohydrates, protein content or diet glycemic index have been also shown to decrease the progression of CVD in obese patients. In this review, we will focus on the positive effects and possible mechanisms of action of these strategies on vascular dysfunction.


Item Type:Article
Uncontrolled Keywords:caloric restriction; dietary intervention; endothelial dysfunction; cardiovascular disease; obesity
Subjects:Medical sciences > Medicine > Endocrinology
Medical sciences > Pharmacy > Dietetics and nutrition
ID Code:70227
Deposited On:09 Feb 2022 12:04
Last Modified:09 Feb 2022 14:56

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