Geometrical limits for UV-C inactivation of pathogens



Downloads per month over past year

Quintana Benito, Jaime and Álvarez Fernández-Balbuena, Antonio and Martínez Antón, Juan Carlos and Vázquez Moliní, Daniel and Prada, Luis and Estrada, Luis and Alda Serrano, Javier (2022) Geometrical limits for UV-C inactivation of pathogens. Optik, 250 . p. 168269. ISSN 0030-4026

[thumbnail of 1-s2.0-S0030402621017897-main.pdf]
Creative Commons Attribution.


Official URL:


The inactivation of pathogens through the irradiation of ultraviolet light depends on how light propagates within the medium where the microorganism is immersed. A simple geometrical optics analysis, and a fluence evaluation reveal some reservoirs where the pathogen may hide and be weakly exposed to the incoming radiation. This geometrical hide-outs also generate a tail in the plot of the total inactivation plot vs. the incoming fluence. We have analyzed these facts using geometrical optics principles and illumination engineering computational packages. The results obtained from previous biomedical measurements involving SARS-CoV-2 have been used to evaluate the inactivation degree for an spherical geometry applicable to airborne pathogens, and for an spherical cap geometry similar to that used in biomedical experiments. The case presented here can be seen as the worst-case scenario applicable under collimated illumination.

Item Type:Article
Additional Information:

CRUE-CSIC (Acuerdos Transformativos 2021)

Uncontrolled Keywords:Geometrical optics, Ultraviolet light, Optical disinfection, Radiometry
Subjects:Medical sciences > Optics > Geometrical and instumental optics
ID Code:70350
Deposited On:11 Feb 2022 16:29
Last Modified:18 Oct 2022 08:51

Origin of downloads

Repository Staff Only: item control page