Incidence, Outcomes and Sex-Related Disparities in Pneumonia: A Matched-Pair Analysis with Data from Spanish Hospitals (2016–2019)

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Miguel Yanes, José María de and López de Andrés, Ana and Jiménez García, Rodrigo and Hernández Barrera, Valentín and Miguel Díez, Javier de and Carabantes Alarcón, David and Pérez Farinós, Napoleón and Wärnberg, Julia (2021) Incidence, Outcomes and Sex-Related Disparities in Pneumonia: A Matched-Pair Analysis with Data from Spanish Hospitals (2016–2019). Journal of Clinical Medicine, 10 (19). p. 4339. ISSN 2077-0383

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Official URL: https://doi.org/10.3390/jcm10194339




Abstract

(1) Background: the purpose of this study is to analyze the incidence and in-hospital mortality (IHM) of community-acquired pneumonia (CAP) needing hospital admission and hospital-acquired pneumonia (HAP) in Spain (2016–2019).
(2) Methods: using the Spanish Register of Specialized Care-Basic Minimum Database, we estimated the incidence of CAP and HAP. We matched each woman with a man with an identical age, according to comorbidities.
(3) Results: we analyzed 518,838 cases of CAP and 38,705 cases of HAP, and 5192 ventilator-associated HAPs (13.4%). The incidence of CAP increased over time in both men (from 384.5 to 449.8 cases/105 population) and women (from 244.9 to 301.2 cases/105 population). Men showed a 47% higher adjusted incidence of CAP than women. The incidence of HAP increased over time in both men (from 302.3 to 342.2 cases/105 population) and women (from 139.2 to 167.6 cases/105 population). Men showed a 98% higher adjusted incidence of HAP than women. IHM was higher in men admitted for CAP than in women (12.9% vs. 12.2%; p < 0.001), but not in men who developed HAP (28.9% vs. 28.0%; p = 0.107). Men admitted for CAP (OR: 1.13; 95% CI: 1.10–1.15) and men who developed HAP (OR: 1.05; 95% CI: 1.01–1.10) had higher IHM than women.
(4) Conclusions: men had higher incidence rates of CAP and HAP than women. Men admitted for CAP and men who developed HAP had higher IHM than women.


Item Type:Article
Uncontrolled Keywords:community-acquired pneumonia; hospital-acquired pneumonia; ventilator-associated pneumonia; gender; sex differences; in-hospital mortality
Subjects:Medical sciences > Medicine > Pneumology
Medical sciences > Medicine > Public health
ID Code:71289
Deposited On:24 Mar 2022 17:38
Last Modified:26 Mar 2022 12:16

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