Community-Acquired Pneumonia among Patients with COPD in Spain from 2016 to 2019. Cohort Study Assessing Sex Differences in the Incidence and Outcomes Using Hospital Discharge Data

Impacto

Downloads

Downloads per month over past year

Miguel Díez, Javier de and López Herranz, Marta and Hernández Barrera, Valentín and Miguel Yanes, Jose M. de and Pérez Farinós, Napoleón and Wärnberg, Julia and Carabantes Alarcón, David and Jiménez García, Rodrigo and López de Andrés, Ana (2021) Community-Acquired Pneumonia among Patients with COPD in Spain from 2016 to 2019. Cohort Study Assessing Sex Differences in the Incidence and Outcomes Using Hospital Discharge Data. Journal of Clinical Medicine, 10 (21). p. 4889. ISSN 2077-0383

[thumbnail of jcm-10-04889-v2.pdf]
Preview
PDF
Creative Commons Attribution.

283kB

Official URL: https://doi.org/10.3390/jcm10214889




Abstract

Background: To describe and analyze the incidence and hospital outcomes of patients admitted with community-acquired pneumonia (CAP) according to Chronic Obstructive Pulmonary Disease (COPD) status and sex in Spanish hospitals from 2016 to 2019.
Methods: We conducted a cohort study using national hospital discharge data of all patients ≥40 years with CAP.
Results: A total of 500,833 patients (59.0% men) was identified. Incidence of CAP increased over time. Age-adjusted incidence was 4.42-times higher in COPD patients. In-hospital mortality (IHM) was lower in men and women with COPD than in those without COPD (14.41% vs. 10.70% in men; 11.12% vs. 8.58%. in women; p < 0.001). The risk of dying in hospital increased with age, presence of several comorbidities (excluding T2DM that was a protective factor), and need for mechanical ventilation (non-invasive and invasive) during admission, irrespective of sex. Over time, the IHM decreased significantly in men and women with COPD. Men with COPD were significantly more likely to die in hospital than were COPD women (OR 1.13; 95% CI 1.07–1.21).
Conclusions: Incidence of CAP was higher among subjects with COPD, although the effect of COPD was higher in men than in women. By contrast, IHM was lower in COPD patients, but men with COPD were significantly more likely to die in hospital than were COPD women.


Item Type:Article
Uncontrolled Keywords:community-acquired pneumonia; COPD; sex; incidence; in-hospital mortality
Subjects:Medical sciences > Medicine > Pneumology
Medical sciences > Nursing > Nursing
ID Code:71295
Deposited On:23 Mar 2022 16:26
Last Modified:24 Mar 2022 08:14

Origin of downloads

Repository Staff Only: item control page