Medical Versus Surgical Treatment for the Management of Diabetic Foot Osteomyelitis: A Systematic Review

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Tardáguila García, Aroa and Sanz Corbalán, Irene and García Alamino, Josep M. and Ahluwalia, Raju and Uccioli, Luigi and Lázaro Martínez, José Luis (2021) Medical Versus Surgical Treatment for the Management of Diabetic Foot Osteomyelitis: A Systematic Review. Journal of Clinical Medicine, 10 (6). p. 1237. ISSN 2077-0383

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Official URL: https://doi.org/10.3390/jcm10061237




Abstract

A systematic review and quality assessment was performed to assess the management of diabetic foot osteomyelitis by medical or surgical treatment. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist was used. All selected studies were evaluated using the Cochrane Risk of Bias Tool to assess the risk of bias for randomized controlled trials. The literature was revised using PubMed (Medline) and Embase (Elsevier) up to September 2020 to identify clinical trials assessing medical or surgical treatment to manage diabetic foot osteomyelitis. A total of six clinical trials that met our inclusion criteria, with a total of 308 participants. Healing rate, complete closure of the wound, and type of complications were the outcomes evaluated. Risk of bias assessment showed that only two of the six clinical trials included in the systematic review had a low risk of bias. Based on our findings, we believe that the management of diabetic foot osteomyelitis remains challenging. There are few high-quality clinical trials that both stratify clinical presentations and compare these treatments. We conclude that the available evidence is insufficient to identify the best option to cure diabetic foot osteomyelitis.


Item Type:Article
Uncontrolled Keywords:diabetic foot osteomyelitis (DFO); medical treatment; surgical treatment; systematic review
Subjects:Medical sciences > Nursing > Podiatry
ID Code:71305
Deposited On:21 Mar 2022 15:17
Last Modified:21 Mar 2022 15:42

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