Trends in Incidence and Outcomes of Hospitalizations for Urinary Tract Infection among Older People in Spain (2001–2018)



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Palacios Ceña, Domingo and Florencio, Lidiane Lima and Hernández Barrera, Valentín and Fernández de las Peñas, César and Miguel Díez, Javier de and Martínez Hernández, David and Carabantes Alarcón, David and Jiménez García, Rodrigo and López de Andrés, Ana and López Herranz, Marta (2021) Trends in Incidence and Outcomes of Hospitalizations for Urinary Tract Infection among Older People in Spain (2001–2018). Journal of Clinical Medicine, 10 (11). p. 2332. ISSN 2077-0383

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(1) Background: To assess time trends in the incidence and in-hospital outcomes of urinary tract infection (UTI) in older people (≥65 years) in Spain (2001–2018) according to sex and to identify the factors independently associated with in-hospital mortality (IHM). (2) Methods: Using the Spanish National Hospital Database, we analyzed comorbidity, procedures, diagnosis, isolated microorganisms, and outcomes. (3) Results: We included 583,693 admissions (56.76% women). In both sexes, the incidence increased with age over time (p < 0.001). In men and women, the highest IHM was found among the oldest patients (>84 years) with values of 9.16% and 8.6%, respectively. The prevalence of bacteremia increased from 4.61% to 4.98% from 2001 to 2018 (p < 0.001) and sepsis decreased from 3.16% to 1.69% (p < 0.001). The risk of dying increased with age (>84 years) (OR 3.63; 95% CI 3.5–3.78) and with almost all comorbidities. Urinary catheter was a risk factor for women (OR 1.1; 95% CI 1.02–1.18) and protective for men (OR 0.71; 95% CI 0.66–0.76). Isolation of Staphylococcus aureus increased the risk of IHM by 40% among men (OR 1.4; 95% CI 1.28–1.53). After adjusting for confounders, IHM decreased over time. (4) Conclusions: The incidence of UTIs was higher in older patients and increased over time; however, IHM decreased during the same period. Female sex, age, comorbidities, sepsis, and a Staphylococcus aureus isolation increased risk of IHM.

Item Type:Article
Uncontrolled Keywords:urinary tract infections; aged; aged 80 and over; incidence; hospital mortality; epidemiologic studies
Subjects:Medical sciences > Medicine > Geriatrics
Medical sciences > Medicine > Nephrology and Urology
ID Code:71315
Deposited On:16 Mar 2022 16:24
Last Modified:17 Mar 2022 08:06

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