Long-Term Results of Single-Anastomosis Duodeno-ileal Bypass with Sleeve Gastrectomy (SADI-S)



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Sánchez Pernaute, Andrés and Rubio Herrera, Miguel Ángel and Pérez Ferré, Natalia and Sáez Rodríguez, Carlos and Marcuello, Clara and Pañella, Clara and Lopez Antoñanzas, Leyre and Torres, Antonio and Pérez Aguirre, Elia (2022) Long-Term Results of Single-Anastomosis Duodeno-ileal Bypass with Sleeve Gastrectomy (SADI-S). Obesity Surgery, 32 (3). pp. 682-689. ISSN 0960-8923

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Official URL: https://doi.org/10.1007/s11695-021-05879-9


Single-anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) is a simplification of the duodenal switch (DS) in which the alimentary limb is eliminated, and the common channel is lengthened from 200 to 300 cm. Short-term results have demonstrated that SADI-S is safe and reproducible and that weight loss and comorbidities resolution are comparable to biliopancreatic diversion or DS.

To analyze the long-term outcomes of SADI-S.

From May 2007 to December 2015, 164 patients were consecutively submitted to a one-step SADI-S. The mean age was 47 years, and the mean body mass index (BMI) was 45.8 kg/m2. A total of 101 patients had type 2 diabetes, 91 arterial hypertension, 81 obstructive apnea, and 118 dyslipidemia. Limb length was 200 cm in 50 cases, 250 cm in 99, and 300 cm in 15.

There was no mortality. One patient had a gastric leak, and 2 patients had an anastomotic leak. A total of 25% of the patients were lost to follow-up at 10 years. Excess weight loss and total weight loss were 87% and 38% at 5 years and 80% and 34% at 10 years. A total of 12 patients were submitted to revisional surgery for hypoproteinemia. Preoperatively 41 diabetics were under insulin treatment; at 5 years, 7 remained with insulin and 12 at 10 years. Mean glycemia was 104 mg/dL at 5 years and 118 mg/dL at 10 years. Mean HbA1c was 5.51% at 5 years and 5.86 at 10 years.

In the long term, SADI-S offers satisfactory weight loss and comorbidities resolution.

Item Type:Article
Additional Information:

CRUE-CSIC (Acuerdos Transformativos 2022)

Uncontrolled Keywords:SADI-S, Duodenal switch, Hypoabsorption, Duodeno-ileostom, Sleeve
Subjects:Medical sciences > Medicine > Gastroenterology and Hepatology
ID Code:72356
Deposited On:24 May 2022 15:11
Last Modified:25 May 2022 07:31

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