HLA in Las Alpujarras Mts., South-East Spain: A Renaissance process of population artificial substitution



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Arnaiz Villena, Antonio and Longas, Javier and Rodríguez Sainz, Carmen and Gómez Casado, Eduardo and Palacio Grüber, José Manuel de and Luna Gómez, Francisco and Moral, Pedro del and Suarez Trujillo, Fabio (2022) HLA in Las Alpujarras Mts., South-East Spain: A Renaissance process of population artificial substitution. Human Immunology, 83 (6). pp. 480-481. ISSN 0198-8859

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Official URL: https://doi.org/10.1016/j.humimm.2022.03.009


Spain was invaded in 711 CE by mostly Berber North Africans carrying Muslim religion to a mostly Christian/Catholic Kingdom. A fight to expel Muslims soon started and were apparently driven out of Iberia (Spain) starting in 1492 CE. However, many of these expelled people were of Iberian old ancestry that had become Muslims at Las Alpujarras Mts. (South-East Spain). Also, Muslim North Africans converted to Christianity either remained there or came back after they more definetively were expelled by 1609 CE. Las Alpujarras region was also repopulated by northern Spaniards mostly from Galicia. Our HLA study of present day Alpujarrans shows that typical North Spain and European Atlantic façade HLA extended haplotypes are very frequent in nowadays Las Alpujarras region, i. e.: HLA-(A*29-B*44)-DRB1*07:01-DQA1*02:01-DQB1*02:01 and (A*02-B*27)-DRB1*15:01-DQA1*01:02-DQB1*06:02. It is concluded that repopulation had a noticeable success even in today Alpujarran population.

Item Type:Article
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CRUE-CSIC (Acuerdos Transformativos 2022)

Uncontrolled Keywords:HLA, Alpujarras, Spaniards, Berbers, Arabs, Repopulation, Muslim,invasion,expulsion
Subjects:Medical sciences > Medicine > Medical genetics
Medical sciences > Biology
Medical sciences > Biology > Genetics
Humanities > History > Middle Ages-History
ID Code:72367
Deposited On:19 May 2022 14:31
Last Modified:18 Oct 2022 08:57

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