Pituitary hormones mRNA abundance in the Mediterranean sea bass Dicentrarchus labrax: seasonal rhythms, effects of melatonin and water salinity

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Falcón, Jack and Herrero, María Jesús and Nisembaum, Laura Gabriela and Isorna Alonso, Esther and Peyric, Elodie and Beauchaud, Marilyn and Attia, Joël and Covès, Denis and Fuentès, Michel and Delgado Saavedra, María Jesús and Besseau, Laurence (2021) Pituitary hormones mRNA abundance in the Mediterranean sea bass Dicentrarchus labrax: seasonal rhythms, effects of melatonin and water salinity. Frontiers in Physiology, 12 (774975). pp. 1-13. ISSN Electronic: 1664-042X

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Official URL: https://doi.org/10.3389/fphys.2021.774975




Abstract

In fish, most hormonal productions of the pituitary gland display daily and/or seasonal rhythmic patterns under control by upstream regulators, including internal biological clocks. The pineal hormone melatonin, one main output of the clocks, acts at different levels of the neuroendocrine axis. Melatonin rhythmic production is synchronized mainly by photoperiod and temperature. Here we aimed at better understanding the role melatonin plays in regulating the pituitary hormonal productions in a species of scientific and economical interest, the euryhaline European sea bass Dicentrarchus labrax. We investigated the seasonal variations in mRNA abundance of pituitary hormones in two groups of fish raised one in sea water (SW fish), and one in brackish water (BW fish). The mRNA abundance of three melatonin receptors was also studied in the SW fish. Finally, we investigated the in vitro effects of melatonin or analogs on the mRNA abundance of pituitary hormones at two times of the year and after adaptation to different salinities. We found that (1) the reproductive hormones displayed similar mRNA seasonal profiles regardless of the fish origin, while (2) the other hormones exhibited different patterns in the SW vs. the BW fish. (3) The melatonin receptors mRNA abundance displayed seasonal variations in the SW fish. (4) Melatonin affected mRNA abundance of most of the pituitary hormones in vitro; (5) the responses to melatonin depended on its concentration, the month investigated and the salinity at which the fish were previously adapted. Our results suggest that the productions of the pituitary are a response to multiple factors from internal and external origin including melatonin. The variety of the responses described might reflect a high plasticity of the pituitary in a fish that faces multiple external conditions along its life characterized by marked daily and seasonal changes in photoperiod, temperature and salinity.


Item Type:Article
Uncontrolled Keywords:Sea bass; Pituitary; Hormones; Annual variations; Melatonin, photoperiod; Salinity
Subjects:Medical sciences > Biology > Animal physiology
Medical sciences > Biology > Fishes
ID Code:72772
Deposited On:09 Jun 2022 10:22
Last Modified:14 Jun 2022 07:30

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