Publication: Análisis de compuestos orgánicos volátiles emitidos por muestras biológicas para el diagnóstico de tuberculosis bovina en jabalíes
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2022-06-17
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Universidad Complutense de Madrid
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Abstract
La tuberculosis bovina (TB) es una enfermedad que ha prevalecido pese a los esfuerzos de los distintos entes gubernamentales globales por erradicarla. La padecen tanto los animales domesticados como los salvajes, pudiéndose transmitir también a los humanos, a través del consumo de alimentos de animales infectados, del contacto con la sangre del animal infectado durante su sacrificio, o a través del aire exhalado por los animales infectados. Los métodos convencionales de identificación de tuberculosis bovina en animales vivos son invasivos. Éstos abarcan la prueba cutánea de tuberculina para el cribado, y la prueba cervical comparativa o el ensayo de liberación de interferón gamma como pruebas complementarias o de confirmación. El diagnóstico final implica el sacrificio del animal para analizar partes afectadas del organismo mediante la necropsia, realizando cultivo en muestras de tejidos. Después de sacrificar al animal, se han evidenciado muchos falsos positivos, lo que acarrea impactos muy negativos...
Bovine tuberculosis (TB) is a disease that has prevailed despite the many efforts of different global government entities to eradicate it. Both domesticated and wild animals can suffer it, and these infected animals can transmit TB to humans through several pathways. These include the consumption of infected food, coming in contact with blood during slaughter, or even with the air exhaled by a diseased animal.Conventional methods of identifying bovine TB in live animals are invasive. These include the tuberculin skin test for screening, and the comparative cervical test or the interferon gamma release test as complementary or confirmatory tests. The final diagnosis involves the sacrifice of the animal to analyze affected parts of the organism through necropsy, performing cell culture on tissue samples. After sacrificing the animal, many false positives are sadly proven, revealing the need to pursue better approaches to this problem...
Bovine tuberculosis (TB) is a disease that has prevailed despite the many efforts of different global government entities to eradicate it. Both domesticated and wild animals can suffer it, and these infected animals can transmit TB to humans through several pathways. These include the consumption of infected food, coming in contact with blood during slaughter, or even with the air exhaled by a diseased animal.Conventional methods of identifying bovine TB in live animals are invasive. These include the tuberculin skin test for screening, and the comparative cervical test or the interferon gamma release test as complementary or confirmatory tests. The final diagnosis involves the sacrifice of the animal to analyze affected parts of the organism through necropsy, performing cell culture on tissue samples. After sacrificing the animal, many false positives are sadly proven, revealing the need to pursue better approaches to this problem...
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Tesis inédita de la Universidad Complutense de Madrid, Facultad de Ciencias Químicas, leída el 11-10-2021