Impacto
Downloads
Downloads per month over past year
Prieto Castañeda, Alejandro and García Garrido, Fernando and Díaz Norambuena, Carolina and Escriche Navarro, Blanca and García Fernández, Alba and Bañuelos, Jorge and Rebollar, Esther and García Moreno, Inmaculada and Martínez Máñez, Ramón and Moya Cerero, Santiago de la and Agarrabeitia, Antonia R. and Ortiz, María J. (2022) Development of Geometry-Controlled All-Orthogonal BODIPY Trimers for Photodynamic Therapy and Phototheragnosis. Organic Letters, 24 (20). pp. 3636-3641. ISSN 1523-7060
Preview |
PDF
Creative Commons Attribution. 1MB |
Official URL: https://doi.org/10.1021/acs.orglett.2c01169
Abstract
We have established an easy synthetic protocol for selectively developing all-orthogonal BODIPY trimers with unprecedented geometries on the basis of selecting methyl oxidation versus electrophilic formylation of key dimeric precursors. Photophysical characterization together with biological assays unraveled the most suitable BODIPY−BODIPY geometrical arrangements within the trimer, forcing them to serve as molecular platforms for the development of new, advanced heavy-atom-free photosensitizers for photodynamic therapy and phototheragnosis.
| Item Type: | Article |
|---|---|
| Additional Information: | CRUE-CSIC (Acuerdos Transformativos 2022) |
| Subjects: | Sciences > Chemistry > Chemistry, Organic |
| ID Code: | 74782 |
| Deposited On: | 05 Oct 2022 06:54 |
| Last Modified: | 05 Oct 2022 08:14 |
Origin of downloads
Repository Staff Only: item control page
