¡Nos trasladamos! E-Prints cerrará el 7 de junio.

En las próximas semanas vamos a migrar nuestro repositorio a una nueva plataforma con muchas funcionalidades nuevas. En esta migración las fechas clave del proceso son las siguientes:

Es muy importante que cualquier depósito se realice en E-Prints Complutense antes del 7 de junio. En caso de urgencia para realizar un depósito, se puede comunicar a docta@ucm.es.

Incidence of Candidemia Is Higher in COVID-19 versus Non-COVID-19 Patients, but Not Driven by Intrahospital Transmission



Downloads per month over past year

Machado, Marina and Estévez, Agustín and Sánchez Carrillo, Carlos and Guinea, Jesús and Escribano, Pilar and Alonso Fernández, Roberto and Valerio, Maricela and Padilla, Belén and Bouza, Emilio and Muñoz, Patricia (2022) Incidence of Candidemia Is Higher in COVID-19 versus Non-COVID-19 Patients, but Not Driven by Intrahospital Transmission. Journal of Fungi, 8 (3). p. 305. ISSN 2309-608X

[thumbnail of jof-08-00305-v3.pdf]
Creative Commons Attribution.


Official URL: https://doi.org/10.3390/jof8030305


There is scarce information on the actual incidence of candidemia in COVID-19 patients. In addition, comparative studies of candidemia episodes in COVID-19 and non-COVID-19 patients are heterogeneous. Here, we assessed the real incidence, epidemiology, and etiology of candidemia in COVID-19 patients, and compared them with those without COVID-19 (2020 vs. 2019 and 2020, respectively). We also genotyped all C. albicans, C. parapsilosis, and C. tropicalis isolates (n = 88), causing candidemia in both groups, providing for the first time a genotypic characterization of isolates gathered in patients with either COVID-19 or non-COVID-19. Incidence of candidemia was higher in patients with COVID-19 than non-COVID-19 (4.73 vs. 0.85 per 1000 admissions; 3.22 vs. 1.14 per 10,000 days of stay). No substantial intergroup differences were found, including mortality. Genotyping proved the presence of a low number of patients involved in clusters, allowing us to rule out rampant patient-to-patient Candida transmission. The four patients, involved in two clusters, had catheter-related candidemia diagnosed in the first COVID-19 wave, which demonstrates breaches in catheter management policies occurring in such an overwhelming situation. In conclusion, the incidence of candidemia in patients with COVID-19 is significantly higher than in those without COVID-19. However, genotyping shows that this increase is not due to uncontrolled intrahospital transmission.

Item Type:Article
Uncontrolled Keywords:COVID-19; candidemia; viral–fungal coinfection; epidemiology; risk factors; invasive fungal infection; invasive candidiasis
Subjects:Medical sciences > Medicine > Communicable diseases
Medical sciences > Medicine > Immunology
Medical sciences > Medicine > Public health
ID Code:75107
Deposited On:20 Oct 2022 11:29
Last Modified:21 Oct 2022 07:21

Origin of downloads

Repository Staff Only: item control page