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The Role of Citicoline and Coenzyme Q10 in Retinal Pathology



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García López, Claudia and García López, Verónica and Matamoros, José A. and Fernández Albarral, José Antonio and García Martín, Elena Salobrar and Hoz Montañana, Rosa de and López Cuenca, Inés and Sánchez Puebla, Lídia and Ramirez Sebastian, Jose Manuel and Ramírez Sebastián, Ana Isabel and Salazar Corral, Juan José (2023) The Role of Citicoline and Coenzyme Q10 in Retinal Pathology. International Journal of Molecular Sciences, 24 (6). 23 p.. ISSN 1422-0067

[thumbnail of 2023 Int J Mol Sci 24 (5072) - The role of citicoline and Coenzyme Q10.pdf]
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Official URL: https://doi.org/10.3390/ijms24065072


Ocular neurodegenerative diseases such as glaucoma, diabetic retinopathy, and age-related macular degeneration are common retinal diseases responsible for most of the blindness causes in the working-age and elderly populations in developed countries. Many of the current treatments used in these pathologies fail to stop or slow the progression of the disease. Therefore, other types of treatments with neuroprotective characteristics may be necessary to allow a more satisfactory management of the disease. Citicoline and coenzyme Q10 are molecules that have neuroprotective, antioxidant, and anti-inflammatory properties, and their use could have a beneficial effect in ocular neurodegenerative pathologies. This review provides a compilation, mainly from the last 10 years, of the main studies that have been published on the use of these drugs in these neurodegenerative diseases of the retina, analyzing the usefulness of these drugs in these pathologies.

Item Type:Article
Additional Information:

Received: 2 December 2022 / Revised: 16 February 2023 / Accepted: 5 March 2023 / Published: 7 March 2023
(This article belongs to the Special Issue Advances in Ocular Pharmacology and Therapeutics)

Uncontrolled Keywords:citicoline; coenzyme Q10; CoQ10; eye; retina; glaucoma; non-arteritic ischemic optic neuropathy; age-related macular degeneration; diabetic retinopathy
Subjects:Medical sciences > Medicine > Neurosciences
Medical sciences > Medicine > Ophtalmology
ID Code:77014
Deposited On:14 Mar 2023 18:31
Last Modified:14 Mar 2023 18:33

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