A Comparative Study of Two Imaging Techniques of Meibomian Glands



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Diz Arias, Elena and Fernández Jiménez, Elena and Peral Cerdá, Assumpta and Gómez Pedrero, José Antonio (2023) A Comparative Study of Two Imaging Techniques of Meibomian Glands. Life, 13 (3). 11 p.. ISSN 2075-1729

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Official URL: https://doi.org/10.3390/life13030791


In the present study, two different meibographers, Oculus Keratograph 5M (K5M) that uses 840 nm infrared light and the Visible Light Non-Contact Meibographer (VLNCM) that uses 610 nm visible light have been used to obtain meibography images from normal and Meibomian Gland Dysfunction (MGD) population. The main objective has been to validate and demonstrate that the use of visible light is useful for observation and quantification of MG in clinical practice. Twenty participants were enrolled in this prospective study. The upper eyelids of one randomly chosen eye were used to obtain results. Forty images were captured and analysed. Three specialized observers were recruited to grade images using Pult and Riede Pult 5-degree scale, in two different sessions. Intra-observer agreement between sessions for both devices was shown. Inter-observer variability analysis showed discrepancy between meiboscores obtained from observers with K5M (p-value < 0.05), except for session 2 in the pathology group, while no statistical difference was found with VLNCM. Repeatability analysis found no statistically significant differences between sessions. Correlation between meibographers showed no statistically significant difference and a moderate correlation coefficient between meiboscores graded with the two devices. The current study suggests that VLNCM can allow MG to be properly visualized and classified in the upper eyelids.

Item Type:Article
Additional Information:

Received: 6 February 2023; Revised: 28 February 2023; Accepted: 13 March 2023; Published: 15 March 2023

Uncontrolled Keywords:meibomian glands; meibography; meibographer; meibomian gland dysfunction; ocular surface
Subjects:Medical sciences > Optics > Eyes anatomy
Medical sciences > Optics > Imaging systems
ID Code:77163
Deposited On:29 Mar 2023 18:18
Last Modified:29 Mar 2023 18:18

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