Publication: Base de datos normativa del grosor de las capas internas de la retina medido con OCT-Spectralis
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2018-11-26
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Universidad Complutense de Madrid
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Abstract
El glaucoma es una de las causas más frecuentes de ceguera irreversible en los países desarrollados. Su patogenia se caracteriza por una pérdida progresiva de células ganglionares de la retina, que se traduce en una pérdida progresiva de campo visual yque en fases avanzadas puede conducir a la ceguera[1]. Dado el carácter irreversible dela enfermedad es muy importante detectar los cambios glaucomatosos de manera fiable tan pronto como sea posible.La llegada de los Tomógrafos de Coherencia Óptica (OCT) ha supuesto un gran cambio en el manejo y diagnóstico de las patologías retinianas y del glaucoma. El OCT es unmétodo de imagen transpupilar y no invasivo, con el que se obtienen imágenestransversales del tejido retiniano que han demostrado tener buena correlación con la histología retiniana[2], [3]. Con los nuevos OCT de dominio espectral es posible adquirir imágenes más rápido y de mejor calidad, si los comparamos con los OCT de dominio tiempo.[4] La última versión del Software del Spectralis SD-OCT (HeildelbergEngineering) permite segmentar de manera automática las capas de la retina de manera individual (Fig.1), y este análisis ha demostrado recientemente tener una excelente repetibilidad y reproducibilidad en sujetos sanos[5]...
Glaucoma is one of the most frequent causes of irreversible blindness in developedcountries. Its pathogenesis is characterized by a progressive loss of retinal ganglion cellswhich translates into a progressive loss of the visual field, and in advanced stages canlead to blindness [1]. Given the irreversible character of the illness, detecting theglaucomatous changes in a reliable way as soon as possible is very important.The arrival of the Optical Coherence Tomography (OCT) has made a big change on themanagement and diagnosis of retinal pathologies and glaucoma. The OCT is a noninvasivetranspupilar imaging method that performs cross-sectional images of the retinaltissue with a proved good correlation with the retinal histology [2]. With the spectraldomain OCTs is possible to acquire images quicker and higher in quality than with timedomain OCTs. The latest version of the Spectralis SD-OCT software (HeildelbergEngineering) allows the automatic segmentation of the retinal layers individually, andthis analysis has been proven recently to have an excellent repeatability andreproducibility in healthy subjects [5]...
Glaucoma is one of the most frequent causes of irreversible blindness in developedcountries. Its pathogenesis is characterized by a progressive loss of retinal ganglion cellswhich translates into a progressive loss of the visual field, and in advanced stages canlead to blindness [1]. Given the irreversible character of the illness, detecting theglaucomatous changes in a reliable way as soon as possible is very important.The arrival of the Optical Coherence Tomography (OCT) has made a big change on themanagement and diagnosis of retinal pathologies and glaucoma. The OCT is a noninvasivetranspupilar imaging method that performs cross-sectional images of the retinaltissue with a proved good correlation with the retinal histology [2]. With the spectraldomain OCTs is possible to acquire images quicker and higher in quality than with timedomain OCTs. The latest version of the Spectralis SD-OCT software (HeildelbergEngineering) allows the automatic segmentation of the retinal layers individually, andthis analysis has been proven recently to have an excellent repeatability andreproducibility in healthy subjects [5]...
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Tesis de la Universidad Complutense de Madrid, Facultad de Medicina, Departamento de Oftalmología y Otorrinolaringología, leída el 20-02-2018