Publication: Susceptibilidad mendeliana a las infecciones por micobacterias en el hombre
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2019-05-29
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Universidad Complutense de Madrid
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Abstract
Desde que Robert Koch descubriera Mycobacterium tuberculosis en 1882 hasta hoy, más de 150 especies del género Mycobacterium han sido descritas. Algunas micobacterias son virulentas y provocan enfermedades en multitud de individuos. Sin embargo, la mayoría de las micobacterias son poco virulentas y pueden encontrarse en el medio ambiente, por lo que son llamadas micobacterias ambientales. Las enfermedades por micobacterias en el humano pueden estar causadas por la virulencia del microorganismo o por una susceptibilidad a las micobacterias intrínseca del individuo, conocida como inmunodeficiencia. Las inmunodeficiencias pueden ser secundarias (también llamadas adquiridas) o primarias, dependiendo de si la infección por micobacteria es una consecuencia indirecta o directa del defecto...
Since the discovery of Mycobacterium tuberculosis in 1882 by Robert Koch, more than 150 species from the genus Mycobacterium have been described. A few of these mycobacteria are virulent and cause disease in many individuals. However, most mycobacteria are environmental mycobacteria, weakly virulent and found regularly in the environment. Mycobacterial diseases in human can be caused by the virulence of the microorganism or because the individual has an affection that renders them susceptible to the mycobacterial infection, known as immunodeficiencies. Immunodeficiencies can be secondary (also known as acquired) or primary, depending if the mycobacterial disease is an indirect or direct consequence of the defect...
Since the discovery of Mycobacterium tuberculosis in 1882 by Robert Koch, more than 150 species from the genus Mycobacterium have been described. A few of these mycobacteria are virulent and cause disease in many individuals. However, most mycobacteria are environmental mycobacteria, weakly virulent and found regularly in the environment. Mycobacterial diseases in human can be caused by the virulence of the microorganism or because the individual has an affection that renders them susceptible to the mycobacterial infection, known as immunodeficiencies. Immunodeficiencies can be secondary (also known as acquired) or primary, depending if the mycobacterial disease is an indirect or direct consequence of the defect...
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Tesis de la Universidad Complutense de Madrid, Facultad de Medicina, Departamento de Microbiología I, leída el 15/02/2019