Publication: Atención farmacéutica en pacientes con dermatitis atópica
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2020-03-30
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Universidad Complutense de Madrid
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Abstract
La dermatitis atópica es una enfermedad inflamatoria crónica de la piel que se desarrolla en forma de brotes caracterizados por cinco síntomas: sequedad cutánea, picor, eritema, inflamación, y formación de eczemas 1. Su origen es multifactorial; intervienen factores genéticos que producen la respuesta de los linfocitos TH2 aumentando los niveles de imnunoglobulinas E, otros factores genéticos que alteran las proteínas estructurales de la piel, factores ambientales de diversos tipos, y la alteración del microbioma cutáneo 25. La prevalencia de la patología estima que de cada 100 niños que nacen en España, 25 desarrollarán dermatitis atópica. Esta enfermedad afecta al 10-20% de los niños y al 3-8% de los adultos en Europa Occidental y Estados Unidos. Además, la dermatitis atópica es una de las patologías más frecuentes en las urgencias y consultas dermatológicas 2-4, y supone un elevado coste socio-económico...
Atopic dermatitis is a chronic inflammatory skin disease that develops in the form of outbreaks characterized by five symptoms: dry skin, itching, erythema, inflammation, and the formation of eczema 1. Its origin is multifactorial; genetic factors that produce the response of the TH2 lymphocytes increasing the levels of immunoglobulins E, other genetic factors that alter the stratum corneum proteins of the skin, environmental factors of various types, and the alteration of the cutaneous microbiome 25.The prevalence of the pathology estimates that out of every 100 children born in Spain, 25 will develop atopic dermatitis. This disease affects 10-20% of children and 3-8% of adults in Western Europe and the United States. In addition, atopic dermatitis is one of the most frequent pathologies in the emergency rooms and dermatological appointments 2-4, entailing a high socio-economic cost...
Atopic dermatitis is a chronic inflammatory skin disease that develops in the form of outbreaks characterized by five symptoms: dry skin, itching, erythema, inflammation, and the formation of eczema 1. Its origin is multifactorial; genetic factors that produce the response of the TH2 lymphocytes increasing the levels of immunoglobulins E, other genetic factors that alter the stratum corneum proteins of the skin, environmental factors of various types, and the alteration of the cutaneous microbiome 25.The prevalence of the pathology estimates that out of every 100 children born in Spain, 25 will develop atopic dermatitis. This disease affects 10-20% of children and 3-8% of adults in Western Europe and the United States. In addition, atopic dermatitis is one of the most frequent pathologies in the emergency rooms and dermatological appointments 2-4, entailing a high socio-economic cost...
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Tesis inédita de la Universidad Complutense de Madrid, Facultad de Farmacia, leída el 20/11/2019