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Identificación de factores de virulencia determinantes de necrosis en infecciones compatibles planta-virus y su papel en la respuesta a estreses abióticos asociados al cambio climático

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2018-09-12
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Universidad Complutense de Madrid
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Las infecciones múltiples de virus en un hospedador compatible son habituales en la naturaleza; de hecho, constituyen más bien la norma. Cuando más de un virus se establece en un mismo hospedador, pueden tener lugar una serie de interacciones que, en su mayoría, presentan implicaciones epidemiológicas y patológicas pobremente caracterizadas, frecuentemente imprevisibles, y ampliamente dependiente de factores ambientales. Entre estos factores ambientales se encuentran precisamente la [CO2] en la atmósfera, la T y la disponibilidad de agua, cuyos valores se encuentran en permanente cambio como consecuencia de la actividad humana y del calentamiento global asociado...
This PhD Thesis exposes and discusses research work consisting of the following topics: i) the viral factor responsible for systemic necrosis elicited during viral synergistic interactions between PVX (Potato virus X, a potexvirus) and viruses belonging to Potyvirus genus, and ii) the effect of environmental stresses associated to climate change, such as high levels of CO2 in the atmosphere ([CO2]), elevated temperatures (T) or drought, on the outcome of compatible plant-virus interactions, on single or mixed infections, with viruses taking part in the PVX-potyvirus interaction mentioned above, or chimeric viruses deriving from them.Mixed infections in a compatible host are common phenomena in nature; in fact, they are the rule rather than the exception. A number of different viral interactions can take place when several viruses are established in the same host. These interactions have epidemiological and pathological implications that are poorly characterized, frequently unpredictable, and largely influenced by environmental factors. Among these environmental factors are [CO2] in the atmosphere, T and water availability, whose values are continuously being modified as a result of human activities and the associated global warming...
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Tesis de la Universidad Complutense de Madrid, Facultad de Ciencias Químicas, Departamento de Bioquímica y Biología Molecular I, leída el 21-06-2017
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