Publication: Impacto diagnóstico del realce parenquimatoso de fondo de la 5ª edición del sistema Bi-Rads®
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2019-11-12
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Universidad Complutense de Madrid
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Abstract
El realce parenquimatoso de fondo (RPF) se refiere a la captación fisiológicanormal del parénquima fibroglandular en resonancia magnética (RM). Se sabe que es una característica dinámica, pero aún se conoce poco sobre cómo se produce y qué factores pueden modificarlo. Recientemente se ha investigado su posible papel como biomarcador en distintos contextos clínicos. El principal objetivo de este estudio es determinar el efecto del RPF en la precisión de la RM de estadificación para detectar cáncer de mama adicional. Si bien se han considerado otros objetivos secundarios, con el fin de ampliar el conocimiento existente sobre el RPF, tales como analizar su posible relación con la edad, situación hormonal y cantidad de tejido fibroglandular (TFG) de las pacientes, así como con las características del tumor diagnosticado...
Background parenchymal enhancement (BPE) on breast magnetic resonance imaging (MRI) refers to normal enhancement of the patient´s fibroglandular tissue after contrast injection. It is known to be a dynamic characteristic, but little is known about how occurs and what factors modify it. Furthermore, recent publications have reported that BPE may play an important role as a biomarker in different clinical settings.The main objective of this study was to determine the impact of BPE on accuracy of preoperative MRI in breast cancer patients. Moreover, in order to broaden the knowledge about the BPE, secondary aims of this work include the assessment of its potential relationship with age, menopausal status and amount of fibroglandular tissue (FGT), as well as other breast cancer characteristics...
Background parenchymal enhancement (BPE) on breast magnetic resonance imaging (MRI) refers to normal enhancement of the patient´s fibroglandular tissue after contrast injection. It is known to be a dynamic characteristic, but little is known about how occurs and what factors modify it. Furthermore, recent publications have reported that BPE may play an important role as a biomarker in different clinical settings.The main objective of this study was to determine the impact of BPE on accuracy of preoperative MRI in breast cancer patients. Moreover, in order to broaden the knowledge about the BPE, secondary aims of this work include the assessment of its potential relationship with age, menopausal status and amount of fibroglandular tissue (FGT), as well as other breast cancer characteristics...
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Tesis inédita de la Universidad Complutense de Madrid, Facultad de Medicina, Departamento de Radiología, rehabilitación y Fisioterapia, leída el 12-07-2019